Variants of the melanocortin-1 receptor: do they matter clinically?

Haddadeen, Ciara; Lai, Chester; Cho, Shin-Young; Healy, Eugene

Haddadeen, Ciara; Lai, Chester; Cho, Shin-Young; Healy, Eugene.

Affiliation

Haddadeen C; Dermatopharmacology, Sir Henry Wellcome Laboratories, Faculty of Medicine, University of Southampton, Southampton, UK; Dermatology, University Hospital Southampton NHS Foundation Trust, Southampton, UK.

Exp Dermatol ; 24(1): 5-9, 2015 Jan.

Article in En | MEDLINE | ID: mdl-25219681

Subject(s)

Carcinoma, Basal Cell/metabolism; Carcinoma, Squamous Cell/metabolism; Pigmentation; Receptor, Melanocortin, Type 1/genetics; Skin Neoplasms/metabolism; Vitiligo/metabolism; alpha-MSH/metabolism; Carcinoma, Basal Cell/genetics; Genetic Variation; Humans; Light; Melanocytes/drug effects; Melanoma/genetics; Melanoma/metabolism; Phenotype; Pigmentation Disorders/genetics; Pigmentation Disorders/metabolism; Receptor, Melanocortin, Type 1/metabolism; Signal Transduction; Skin/radiation effects; Skin Neoplasms/genetics; Skin Pigmentation/physiology; Ultraviolet Rays; Vitiligo/genetics; alpha-MSH/pharmacology

Key words

alpha-melanocyte stimulating hormone; basal cell carcinoma; evolution; melanocortin 1 receptor; melanoma; pigmentation; red hair; skin type; squamous cell carcinoma; vitiligo

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin Neoplasms / Vitiligo / Pigmentation / Alpha-MSH / Carcinoma, Basal Cell / Carcinoma, Squamous Cell / Receptor, Melanocortin, Type 1 Limits: Humans Language: En Journal: Exp Dermatol Journal subject: DERMATOLOGIA Year: 2015 Document type: Article Affiliation country: United kingdom

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