A role for the sodium pump in H2O2-induced vasorelaxation in porcine isolated coronary arteries.

Wong, P S; Garle, M J; Alexander, S P H; Randall, M D; Roberts, R E

Wong, P S; Garle, M J; Alexander, S P H; Randall, M D; Roberts, R E.

Affiliation

Wong PS; Pharmacology Research Group, School of Life Sciences, University of Nottingham Medical School, Queen's Medical Centre, Nottingham NG7 2UH, United Kingdom.
Garle MJ; Pharmacology Research Group, School of Life Sciences, University of Nottingham Medical School, Queen's Medical Centre, Nottingham NG7 2UH, United Kingdom.
Alexander SP; Pharmacology Research Group, School of Life Sciences, University of Nottingham Medical School, Queen's Medical Centre, Nottingham NG7 2UH, United Kingdom.
Randall MD; Pharmacology Research Group, School of Life Sciences, University of Nottingham Medical School, Queen's Medical Centre, Nottingham NG7 2UH, United Kingdom. Electronic address: michael.randall@nottingham.ac.uk.
Roberts RE; Pharmacology Research Group, School of Life Sciences, University of Nottingham Medical School, Queen's Medical Centre, Nottingham NG7 2UH, United Kingdom.

Pharmacol Res ; 90: 25-35, 2014 Dec.

Article in En | MEDLINE | ID: mdl-25258292

Subject(s)

Coronary Vessels/physiology; Hydrogen Peroxide/pharmacology; Sodium-Potassium-Exchanging ATPase/physiology; Vasodilation/drug effects; Animals; Bradykinin/pharmacology; Carbenoxolone/pharmacology; Catalase/pharmacology; Colforsin/pharmacology; Coronary Vessels/drug effects; Female; In Vitro Techniques; Indomethacin/pharmacology; Male; NG-Nitroarginine Methyl Ester/pharmacology; Nitroprusside/pharmacology; Ouabain/pharmacology; Oxadiazoles/pharmacology; Peptides/pharmacology; Polyethylene Glycols/pharmacology; Quinoxalines/pharmacology; Sodium-Potassium-Exchanging ATPase/antagonists & inhibitors; Swine; Vasoconstrictor Agents/pharmacology; Vasodilation/physiology; Verapamil/pharmacology

Key words

Bradykinin (PubChem CID: 6026); Ca(2+)-reintroduction; Calcium chloride (PubChem CID: 6093260); Glibenclamide (PubChem CID: 3488); Hydrogen peroxide (H(2)O(2)) relaxation; Hydrogen peroxide (PubChem CID: 784); Indomethacin (PubChem CID: 3715); KCl relaxation; Ouabain (PubChem CID: 439501); Ouabain-sensitive sodiumpotassium pump; Porcine coronary artery; Rubidium chloride (PubChem CID: 62683); Rubidium uptake; Tetraethylammonium acetate tetrahydrate (PubChem CID: 2724098); U46619, 9,11-dideoxy-9α,11α-epoxymethanoprostaglandin F(2α) (PubChem CID: 16760624); l-NAME (PubChem CID: 39836)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vasodilation / Sodium-Potassium-Exchanging ATPase / Coronary Vessels / Hydrogen Peroxide Limits: Animals Language: En Journal: Pharmacol Res Journal subject: FARMACOLOGIA Year: 2014 Document type: Article Affiliation country: United kingdom Country of publication: Netherlands

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