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Oral administration of the broad-spectrum antibiofilm compound toremifene inhibits Candida albicans and Staphylococcus aureus biofilm formation in vivo.
De Cremer, Kaat; Delattin, Nicolas; De Brucker, Katrijn; Peeters, Annelies; Kucharíková, Soña; Gerits, Evelien; Verstraeten, Natalie; Michiels, Jan; Van Dijck, Patrick; Cammue, Bruno P A; Thevissen, Karin.
Affiliation
  • De Cremer K; Centre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium Department of Plant Systems Biology, VIB, Ghent, Belgium.
  • Delattin N; Centre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.
  • De Brucker K; Centre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.
  • Peeters A; Centre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.
  • Kucharíková S; Department of Molecular Microbiology, VIB, KU Leuven, Leuven, Belgium Laboratory of Molecular Cell Biology, KU Leuven, Leuven, Belgium.
  • Gerits E; Centre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.
  • Verstraeten N; Centre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.
  • Michiels J; Centre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.
  • Van Dijck P; Department of Molecular Microbiology, VIB, KU Leuven, Leuven, Belgium Laboratory of Molecular Cell Biology, KU Leuven, Leuven, Belgium.
  • Cammue BP; Centre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium Department of Plant Systems Biology, VIB, Ghent, Belgium Bruno.Cammue@biw.kuleuven.be.
  • Thevissen K; Centre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.
Antimicrob Agents Chemother ; 58(12): 7606-10, 2014 Dec.
Article in En | MEDLINE | ID: mdl-25288093

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pseudomonas Infections / Staphylococcal Infections / Candidiasis, Cutaneous / Toremifene / Biofilms / Selective Estrogen Receptor Modulators / Anti-Infective Agents Limits: Animals Language: En Journal: Antimicrob Agents Chemother Year: 2014 Document type: Article Affiliation country: Belgium

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pseudomonas Infections / Staphylococcal Infections / Candidiasis, Cutaneous / Toremifene / Biofilms / Selective Estrogen Receptor Modulators / Anti-Infective Agents Limits: Animals Language: En Journal: Antimicrob Agents Chemother Year: 2014 Document type: Article Affiliation country: Belgium