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Hepatitis C core antigen testing: a reliable, quick, and potentially cost-effective alternative to hepatitis C polymerase chain reaction in diagnosing acute hepatitis C virus infection.
Cresswell, Fiona V; Fisher, Martin; Hughes, Daniel J; Shaw, Simon G; Homer, Gary; Hassan-Ibrahim, Mohammed O.
Affiliation
  • Cresswell FV; Lawson Unit, Department of HIV and Sexual Health, Royal Sussex County Hospital.
  • Fisher M; Lawson Unit, Department of HIV and Sexual Health, Royal Sussex County Hospital Brighton and Sussex Medical School.
  • Hughes DJ; Lawson Unit, Department of HIV and Sexual Health, Royal Sussex County Hospital.
  • Shaw SG; Lawson Unit, Department of HIV and Sexual Health, Royal Sussex County Hospital.
  • Homer G; Department of Virology/Microbiology and Infection, Royal Sussex County Hospital, Brighton, United Kingdom.
  • Hassan-Ibrahim MO; Department of Virology/Microbiology and Infection, Royal Sussex County Hospital, Brighton, United Kingdom.
Clin Infect Dis ; 60(2): 263-6, 2015 Jan 15.
Article in En | MEDLINE | ID: mdl-25301216
ABSTRACT
Hepatitis C virus (HCV) is increasingly common among human immunodeficiency virus (HIV)-infected men who have sex with men. We evaluated the efficacy of HCV core antigen in diagnosing acute HCV in an HIV-infected cohort. Compared with HCV polymerase chain reaction, core antigen proved sensitive (100%) and specific (97.9%). As a quick, simple, and cost-effective test, it has considerable utility in screening for acute HCV.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Core Proteins / Hepatitis C / Diagnostic Tests, Routine Type of study: Diagnostic_studies / Evaluation_studies / Health_economic_evaluation Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Clin Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2015 Document type: Article
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Core Proteins / Hepatitis C / Diagnostic Tests, Routine Type of study: Diagnostic_studies / Evaluation_studies / Health_economic_evaluation Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Clin Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2015 Document type: Article