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Cancer-selective targeting of the NF-κB survival pathway with GADD45ß/MKK7 inhibitors.
Tornatore, Laura; Sandomenico, Annamaria; Raimondo, Domenico; Low, Caroline; Rocci, Alberto; Tralau-Stewart, Cathy; Capece, Daria; D'Andrea, Daniel; Bua, Marco; Boyle, Eileen; van Duin, Mark; Zoppoli, Pietro; Jaxa-Chamiec, Albert; Thotakura, Anil K; Dyson, Julian; Walker, Brian A; Leonardi, Antonio; Chambery, Angela; Driessen, Christoph; Sonneveld, Pieter; Morgan, Gareth; Palumbo, Antonio; Tramontano, Anna; Rahemtulla, Amin; Ruvo, Menotti; Franzoso, Guido.
Affiliation
  • Tornatore L; Department of Medicine, Centre for Cell Signalling and Inflammation, Imperial College London, London W12 0NN, UK.
  • Sandomenico A; Institute of Biostructures and Bioimages, National Research Council and CIRPeB, 80134 Naples, Italy.
  • Raimondo D; Department of Physics, "Sapienza" University, 00185 Rome, Italy.
  • Low C; Drug Discovery Centre, Imperial College London, London W6 8RP, UK.
  • Rocci A; Division of Hematology, University of Torino, AOU San Giovanni Battista, 10126 Turin, Italy.
  • Tralau-Stewart C; Drug Discovery Centre, Imperial College London, London W6 8RP, UK.
  • Capece D; Department of Medicine, Centre for Cell Signalling and Inflammation, Imperial College London, London W12 0NN, UK.
  • D'Andrea D; Department of Physics, "Sapienza" University, 00185 Rome, Italy.
  • Bua M; Department of Medicine, Centre for Haematology, Imperial College London, London W12 0NN, UK.
  • Boyle E; Section of Haemato-Oncology, The Institute of Cancer Research, London SM2 5NG, UK.
  • van Duin M; Department of Hematology, Erasmus University Medical Center, 3000 CA Rotterdam, the Netherlands.
  • Zoppoli P; Institute for Cancer Genetics, Columbia University Medical Center, New York, NY 10032, USA.
  • Jaxa-Chamiec A; Drug Discovery Centre, Imperial College London, London W6 8RP, UK.
  • Thotakura AK; Department of Medicine, Centre for Cell Signalling and Inflammation, Imperial College London, London W12 0NN, UK.
  • Dyson J; Department of Medicine, Section of Molecular Immunology, Imperial College London, London W12 0NN, UK.
  • Walker BA; Section of Haemato-Oncology, The Institute of Cancer Research, London SM2 5NG, UK.
  • Leonardi A; Department of Molecular Medicine and Medical Biotechnologies, University of Naples "Federico II," 80131 Naples, Italy.
  • Chambery A; Department of Environmental, Biological, and Pharmaceutical Sciences and Technologies, Second University of Naples, 81100 Caserta, Italy; IRCCS Multimedica, 20138 Milan, Italy.
  • Driessen C; Department of Oncology/Hematology, Kantonsspital St. Gallen, 9007 St. Gallen, Switzerland.
  • Sonneveld P; Department of Hematology, Erasmus University Medical Center, 3000 CA Rotterdam, the Netherlands.
  • Morgan G; Section of Haemato-Oncology, The Institute of Cancer Research, London SM2 5NG, UK.
  • Palumbo A; Division of Hematology, University of Torino, AOU San Giovanni Battista, 10126 Turin, Italy.
  • Tramontano A; Department of Physics, "Sapienza" University, 00185 Rome, Italy; Istituto Pasteur Fondazione Cenci Bolognetti, "Sapienza" University, 00185 Rome, Italy.
  • Rahemtulla A; Department of Medicine, Centre for Haematology, Imperial College London, London W12 0NN, UK.
  • Ruvo M; Institute of Biostructures and Bioimages, National Research Council and CIRPeB, 80134 Naples, Italy. Electronic address: menotti.ruvo@unina.it.
  • Franzoso G; Department of Medicine, Centre for Cell Signalling and Inflammation, Imperial College London, London W12 0NN, UK. Electronic address: g.franzoso@imperial.ac.uk.
Cancer Cell ; 26(4): 495-508, 2014 10 13.
Article in En | MEDLINE | ID: mdl-25314077
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nuclear Proteins / NF-kappa B / Cell Cycle Proteins / MAP Kinase Kinase 7 / Multiple Myeloma Type of study: Prognostic_studies Limits: Humans Language: En Journal: Cancer Cell Journal subject: NEOPLASIAS Year: 2014 Document type: Article Affiliation country: United kingdom Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nuclear Proteins / NF-kappa B / Cell Cycle Proteins / MAP Kinase Kinase 7 / Multiple Myeloma Type of study: Prognostic_studies Limits: Humans Language: En Journal: Cancer Cell Journal subject: NEOPLASIAS Year: 2014 Document type: Article Affiliation country: United kingdom Country of publication: United States