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Syntheses and discovery of a novel class of cinnamic hydroxamates as histone deacetylase inhibitors by multimodality molecular imaging in living subjects.
Chan, C T; Qi, J; Smith, W; Paranol, R; Mazitschek, R; West, N; Reeves, R; Chiosis, G; Schreiber, S L; Bradner, J E; Paulmurugan, R; Gambhir, S S.
Affiliation
  • Chan CT; Department of Radiology, Stanford University School of Medicine, Stanford, California. Molecular Imaging Program at Stanford (MIPS), Stanford University School of Medicine, Stanford, California. Bio-X Program, Stanford University School of Medicine, Stanford, California.
  • Qi J; Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Smith W; Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Paranol R; Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Mazitschek R; Harvard Medical School, Boston, Massachusetts. Massachusetts General Hospital, Boston, Massachusetts. Broad Institute, Cambridge, Massachusetts.
  • West N; Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Reeves R; Department of Radiology, Stanford University School of Medicine, Stanford, California. Molecular Imaging Program at Stanford (MIPS), Stanford University School of Medicine, Stanford, California. Bio-X Program, Stanford University School of Medicine, Stanford, California.
  • Chiosis G; Department of Medicine and Program in Molecular Pharmacology and Medical Chemistry, Memorial Sloan-Kettering Cancer Center, New York, New York.
  • Schreiber SL; Broad Institute, Cambridge, Massachusetts.
  • Bradner JE; Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts. Harvard Medical School, Boston, Massachusetts. Broad Institute, Cambridge, Massachusetts.
  • Paulmurugan R; Department of Radiology, Stanford University School of Medicine, Stanford, California. Molecular Imaging Program at Stanford (MIPS), Stanford University School of Medicine, Stanford, California. Bio-X Program, Stanford University School of Medicine, Stanford, California.
  • Gambhir SS; Department of Radiology, Stanford University School of Medicine, Stanford, California. Molecular Imaging Program at Stanford (MIPS), Stanford University School of Medicine, Stanford, California. Bio-X Program, Stanford University School of Medicine, Stanford, California. Department of Bioengineering
Cancer Res ; 74(24): 7475-86, 2014 Dec 15.
Article in En | MEDLINE | ID: mdl-25320008
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Histone Deacetylase Inhibitors / Molecular Imaging / Multimodal Imaging / Hydroxamic Acids Limits: Animals / Humans Language: En Journal: Cancer Res Year: 2014 Document type: Article Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Histone Deacetylase Inhibitors / Molecular Imaging / Multimodal Imaging / Hydroxamic Acids Limits: Animals / Humans Language: En Journal: Cancer Res Year: 2014 Document type: Article Country of publication: United States