Dynamic principle for designing antagonistic/agonistic molecules for EphA4 receptor, the only known ALS modifier.

Qin, Haina; Lim, Liang-Zhong; Song, Jianxing

Qin, Haina; Lim, Liang-Zhong; Song, Jianxing.

Affiliation

Qin H; Department of Biological Sciences, Faculty of Science, National University of Singapore , 10 Kent Ridge Crescent, Singapore 119260, Singapore.

ACS Chem Biol ; 10(2): 372-8, 2015 Feb 20.

Article in En | MEDLINE | ID: mdl-25334011

Subject(s)

Amyotrophic Lateral Sclerosis/metabolism; Receptor, EphA4/agonists; Receptor, EphA4/antagonists & inhibitors; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Protein Conformation; Protein Structure, Tertiary

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptor, EphA4 / Amyotrophic Lateral Sclerosis Type of study: Prognostic_studies Limits: Humans Language: En Journal: ACS Chem Biol Year: 2015 Document type: Article Affiliation country: Singapore Country of publication: United States

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