Effect of Ca2EDTA on zinc mediated inflammation and neuronal apoptosis in hippocampus of an in vivo mouse model of hypobaric hypoxia.

Malairaman, Udayabanu; Dandapani, Kumaran; Katyal, Anju

Malairaman, Udayabanu; Dandapani, Kumaran; Katyal, Anju.

Affiliation

Malairaman U; Dr.B.R.Ambedkar Center for Biomedical Research, University of Delhi, Delhi, India.
Dandapani K; Dr.B.R.Ambedkar Center for Biomedical Research, University of Delhi, Delhi, India.
Katyal A; Dr.B.R.Ambedkar Center for Biomedical Research, University of Delhi, Delhi, India.

PLoS One ; 9(10): e110253, 2014.

Article in En | MEDLINE | ID: mdl-25340757

Subject(s)

Apoptosis/drug effects; Edetic Acid/pharmacology; Hippocampus/pathology; Hypoxia/pathology; Inflammation/pathology; Neurons/pathology; Zinc/adverse effects; Animals; Apoptosis/genetics; Chelating Agents/pharmacology; Disease Models, Animal; Edetic Acid/administration & dosage; Gene Expression Regulation/drug effects; Homeostasis/drug effects; Homeostasis/genetics; Hypoxia/genetics; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism; In Situ Nick-End Labeling; Inflammation/chemically induced; Inflammation/genetics; Inflammation Mediators/metabolism; Lipid Peroxidation/drug effects; Male; Mice, Inbred BALB C; NADPH Oxidases/metabolism; Neurons/drug effects; Neurons/metabolism; Nitric Oxide/metabolism; Nitrites/metabolism; Poly(ADP-ribose) Polymerases/metabolism; bcl-2-Associated X Protein/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Zinc / Edetic Acid / Apoptosis / Hippocampus / Inflammation / Hypoxia / Neurons Type of study: Prognostic_studies Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2014 Document type: Article Affiliation country: India Country of publication: United States

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