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Phenotypic heterogeneity in IGHV-mutated CLL patients has prognostic impact and identifies a subset with increased sensitivity to BTK and PI3Kδ inhibition.
Pepper, C; Buggins, A G S; Jones, C H; Walsby, E J; Forconi, F; Pratt, G; Devereux, S; Stevenson, F K; Fegan, C.
Affiliation
  • Pepper C; Cardiff CLL Research Group, Institute of Cancer & Genetics, School of Medicine, Cardiff University, Cardiff, UK.
  • Buggins AG; Department of Haematology, King's College London, London, UK.
  • Jones CH; Cardiff CLL Research Group, Institute of Cancer & Genetics, School of Medicine, Cardiff University, Cardiff, UK.
  • Walsby EJ; Cardiff CLL Research Group, Institute of Cancer & Genetics, School of Medicine, Cardiff University, Cardiff, UK.
  • Forconi F; Cancer Sciences Unit, CRUK Clinical Centre, University of Southampton, Southampton, UK.
  • Pratt G; CRUK Institute for Cancer Studies, University of Birmingham, Birmingham, UK.
  • Devereux S; Department of Haematology, King's College London, London, UK.
  • Stevenson FK; Cancer Sciences Unit, CRUK Clinical Centre, University of Southampton, Southampton, UK.
  • Fegan C; Cardiff CLL Research Group, Institute of Cancer & Genetics, School of Medicine, Cardiff University, Cardiff, UK.
Leukemia ; 29(3): 744-7, 2015 Mar.
Article in En | MEDLINE | ID: mdl-25349153
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Lymphocytic, Chronic, B-Cell / Gene Expression Regulation, Neoplastic / Immunoglobulin Heavy Chains / Receptors, CXCR4 / Integrin alpha4 / Antineoplastic Agents Type of study: Diagnostic_studies / Prognostic_studies Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2015 Document type: Article Country of publication: United kingdom
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Lymphocytic, Chronic, B-Cell / Gene Expression Regulation, Neoplastic / Immunoglobulin Heavy Chains / Receptors, CXCR4 / Integrin alpha4 / Antineoplastic Agents Type of study: Diagnostic_studies / Prognostic_studies Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2015 Document type: Article Country of publication: United kingdom