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Preclinical efficacy of MEK inhibition in Nras-mutant AML.
Burgess, Michael R; Hwang, Eugene; Firestone, Ari J; Huang, Tannie; Xu, Jin; Zuber, Johannes; Bohin, Natacha; Wen, Tiffany; Kogan, Scott C; Haigis, Kevin M; Sampath, Deepak; Lowe, Scott; Shannon, Kevin; Li, Qing.
Affiliation
  • Burgess MR; Divisions of Hematology/Oncology, Department of Medicine and.
  • Hwang E; Department of Pediatrics, University of California San Francisco, San Francisco, CA;
  • Firestone AJ; Department of Pediatrics, University of California San Francisco, San Francisco, CA;
  • Huang T; Department of Pediatrics, University of California San Francisco, San Francisco, CA;
  • Xu J; Department of Pediatrics, University of California San Francisco, San Francisco, CA;
  • Zuber J; Research Institute of Molecular Pathology, Vienna, Austria;
  • Bohin N; Department of Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI;
  • Wen T; Department of Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI;
  • Kogan SC; Laboratory Medicine, University of California, San Francisco, San Francisco, CA;
  • Haigis KM; Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA;
  • Sampath D; Department of Translational Oncology, Genentech Inc., South San Francisco, CA;
  • Lowe S; Howard Hughes Medical Institute; Memorial Sloan Kettering Cancer Center, New York, NY; and.
  • Shannon K; Department of Pediatrics, University of California San Francisco, San Francisco, CA; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA.
  • Li Q; Department of Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI;
Blood ; 124(26): 3947-55, 2014 Dec 18.
Article in En | MEDLINE | ID: mdl-25361812
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Monomeric GTP-Binding Proteins / MAP Kinase Kinase Kinases / Mutation Limits: Animals / Humans Language: En Journal: Blood Year: 2014 Document type: Article Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Monomeric GTP-Binding Proteins / MAP Kinase Kinase Kinases / Mutation Limits: Animals / Humans Language: En Journal: Blood Year: 2014 Document type: Article Country of publication: United States