Parathyroid carcinoma with intracranial metastasis at diagnosis in a patient with uncontrolled hypercalcemia.
Ann Clin Lab Sci
; 44(4): 484-8, 2014.
Article
in En
| MEDLINE
| ID: mdl-25361937
ABSTRACT
Parathyroid carcinoma is an uncommon malignancy and a rare cause of primary hyperparathyroidism. Although this tumor is capable of metastasis, metastatic disease is very uncommon intracranially, with only seven cases reported in the literature. When intracranial metastases occur, they typically present months to years following the diagnosis of the primary tumor with hypercalcemia refractory to medical conservative treatment. Aggressive surgical resection of all metastases is necessary for control of the disease. We report a case of metastatic parathyroid carcinoma with two intracranial metastatic foci (in the left frontal lobe and left cerebellar hemisphere) identified at the time of the primary tumor diagnosis in a patient who presented with symptomatic hypercalcemia.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Parathyroid Neoplasms
/
Brain Neoplasms
/
Hypercalcemia
Type of study:
Diagnostic_studies
/
Prognostic_studies
Limits:
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Ann Clin Lab Sci
Year:
2014
Document type:
Article
Affiliation country:
United States