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Crowdsourced analysis of clinical trial data to predict amyotrophic lateral sclerosis progression.
Küffner, Robert; Zach, Neta; Norel, Raquel; Hawe, Johann; Schoenfeld, David; Wang, Liuxia; Li, Guang; Fang, Lilly; Mackey, Lester; Hardiman, Orla; Cudkowicz, Merit; Sherman, Alexander; Ertaylan, Gokhan; Grosse-Wentrup, Moritz; Hothorn, Torsten; van Ligtenberg, Jules; Macke, Jakob H; Meyer, Timm; Schölkopf, Bernhard; Tran, Linh; Vaughan, Rubio; Stolovitzky, Gustavo; Leitner, Melanie L.
Affiliation
  • Küffner R; 1] Institute of Bioinformatics and Systems Biology, German Research Center for Environmental Health, Munich, Germany. [2] Department of Informatics, Ludwig-Maximilians-University, Munich, Germany.
  • Zach N; Prize4Life, Tel Aviv, Israel and Cambridge, Massachusetts, USA.
  • Norel R; IBM T.J. Watson Research Center, Yorktown Heights, New York, USA.
  • Hawe J; Department of Informatics, Ludwig-Maximilians-University, Munich, Germany.
  • Schoenfeld D; 1] MGH Biostatistics Center, Massachusetts General Hospital, Boston, Massachusetts, USA. [2] Harvard Medical School, Charlestown, Massachusetts, USA.
  • Wang L; Sentrana Inc., Washington, DC, USA.
  • Li G; Sentrana Inc., Washington, DC, USA.
  • Fang L; Latham&Watkins LLP, Silicon Valley, California, USA.
  • Mackey L; Department of Statistics, Stanford University, Stanford, California, USA.
  • Hardiman O; Department of Neuroscience, Beaumont Hospital and Trinity College Dublin, Dublin, Ireland.
  • Cudkowicz M; Neurological Clinical Research Institute, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
  • Sherman A; Neurological Clinical Research Institute, Massachusetts General Hospital, Charlestown, Massachusetts, USA.
  • Ertaylan G; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch/Alzette, Luxembourg.
  • Grosse-Wentrup M; Max Planck Institute for Intelligent Systems, Tübingen, Germany.
  • Hothorn T; Institute of Social- and Preventive Medicine, University of Zürich, Zürich, Switzerland.
  • van Ligtenberg J; Orca XL Problem Solvers, Amsterdam, the Netherlands.
  • Macke JH; Max Planck Institute for Biological Cybernetics and Bernstein Center for Computational Neuroscience, Tübingen, Germany.
  • Meyer T; Max Planck Institute for Intelligent Systems, Tübingen, Germany.
  • Schölkopf B; Max Planck Institute for Intelligent Systems, Tübingen, Germany.
  • Tran L; Berkeley School of Public Health, University of California, Berkeley, California, USA.
  • Vaughan R; Orca XL Problem Solvers, Amsterdam, the Netherlands.
  • Stolovitzky G; IBM T.J. Watson Research Center, Yorktown Heights, New York, USA.
  • Leitner ML; 1] Prize4Life, Tel Aviv, Israel and Cambridge, Massachusetts, USA. [2] ALS Innovation Hub, Biogen Idec, Cambridge, Massachusetts, USA.
Nat Biotechnol ; 33(1): 51-7, 2015 Jan.
Article in En | MEDLINE | ID: mdl-25362243
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Clinical Trials as Topic / Crowdsourcing / Amyotrophic Lateral Sclerosis Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Nat Biotechnol Journal subject: BIOTECNOLOGIA Year: 2015 Document type: Article Affiliation country: Germany Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Clinical Trials as Topic / Crowdsourcing / Amyotrophic Lateral Sclerosis Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Nat Biotechnol Journal subject: BIOTECNOLOGIA Year: 2015 Document type: Article Affiliation country: Germany Country of publication: United States