Hippocampal sclerosis in Lewy body disease is a TDP-43 proteinopathy similar to FTLD-TDP Type A.

Aoki, Naoya; Murray, Melissa E; Ogaki, Kotaro; Fujioka, Shinsuke; Rutherford, Nicola J; Rademakers, Rosa; Ross, Owen A; Dickson, Dennis W

Aoki, Naoya; Murray, Melissa E; Ogaki, Kotaro; Fujioka, Shinsuke; Rutherford, Nicola J; Rademakers, Rosa; Ross, Owen A; Dickson, Dennis W.

Affiliation

Aoki N; Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.

Acta Neuropathol ; 129(1): 53-64, 2015 Jan.

Article in En | MEDLINE | ID: mdl-25367383

Subject(s)

Frontotemporal Lobar Degeneration/pathology; Hippocampus/pathology; Lewy Body Disease/pathology; TDP-43 Proteinopathies/pathology; Aged; Aged, 80 and over; Apolipoprotein E4/genetics; DNA-Binding Proteins/metabolism; Female; Frontotemporal Lobar Degeneration/epidemiology; Frontotemporal Lobar Degeneration/genetics; Frontotemporal Lobar Degeneration/metabolism; Hippocampus/metabolism; Humans; Immunohistochemistry; Intercellular Signaling Peptides and Proteins/genetics; Lewy Body Disease/epidemiology; Lewy Body Disease/genetics; Lewy Body Disease/metabolism; Male; Membrane Proteins/genetics; Nerve Tissue Proteins/genetics; Neurites/metabolism; Neurites/pathology; Progranulins; Sclerosis/epidemiology; Sclerosis/genetics; Sclerosis/metabolism; TDP-43 Proteinopathies/epidemiology; TDP-43 Proteinopathies/genetics; TDP-43 Proteinopathies/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lewy Body Disease / Frontotemporal Lobar Degeneration / TDP-43 Proteinopathies / Hippocampus Limits: Aged / Aged80 / Female / Humans / Male Language: En Journal: Acta Neuropathol Year: 2015 Document type: Article Affiliation country: United States Country of publication: Germany

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