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[Pt(O,O'-acac)(γ-acac)(DMS)] alters SH-SY5Y cell migration and invasion by the inhibition of Na+/H+ exchanger isoform 1 occurring through a PKC-ε/ERK/mTOR Pathway.
Muscella, Antonella; Vetrugno, Carla; Calabriso, Nadia; Cossa, Luca Giulio; De Pascali, Sandra Angelica; Fanizzi, Francesco Paolo; Marsigliante, Santo.
Affiliation
  • Muscella A; Cell Pathology Lab, Dipartimento di Scienze e Tecnologie Biologiche e Ambientali (Di.S.Te.B.A.), Salento University, Lecce, Italy.
  • Vetrugno C; Neuropathology Unit, Istituto di Neurologia sperimentale e Divisione di Neuroscienze, Istituto Scientifico IRCCS San Raffaele (sezione di Lecce), Milano, Italy.
  • Calabriso N; Cell Physiology Lab, Dipartimento di Scienze e Tecnologie Biologiche e Ambientali (Di.S.Te.B.A.), Salento University, Lecce, Italy.
  • Cossa LG; Cell Physiology Lab, Dipartimento di Scienze e Tecnologie Biologiche e Ambientali (Di.S.Te.B.A.), Salento University, Lecce, Italy.
  • De Pascali SA; General and Inorganic Chemistry Lab, Dipartimento di Scienze e Tecnologie Biologiche e Ambientali (Di.S.Te.B.A.), Salento University, Lecce, Italy.
  • Fanizzi FP; General and Inorganic Chemistry Lab, Dipartimento di Scienze e Tecnologie Biologiche e Ambientali (Di.S.Te.B.A.), Salento University, Lecce, Italy.
  • Marsigliante S; Cell Physiology Lab, Dipartimento di Scienze e Tecnologie Biologiche e Ambientali (Di.S.Te.B.A.), Salento University, Lecce, Italy.
PLoS One ; 9(11): e112186, 2014.
Article in En | MEDLINE | ID: mdl-25372487
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Movement / Sodium-Hydrogen Exchangers / Platinum Compounds / MAP Kinase Signaling System / Cation Transport Proteins / Extracellular Signal-Regulated MAP Kinases / Protein Kinase C-epsilon / TOR Serine-Threonine Kinases / Neoplasm Proteins / Neuroblastoma Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2014 Document type: Article Affiliation country: Italy Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Movement / Sodium-Hydrogen Exchangers / Platinum Compounds / MAP Kinase Signaling System / Cation Transport Proteins / Extracellular Signal-Regulated MAP Kinases / Protein Kinase C-epsilon / TOR Serine-Threonine Kinases / Neoplasm Proteins / Neuroblastoma Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2014 Document type: Article Affiliation country: Italy Country of publication: United States