Identification of epigenetically inactivated genes in human hepatocellular carcinoma by integrative analyses of methylation profiling and pharmacological unmasking.

Nishida, Naoshi; Chishina, Hirokazu; Arizumi, Tadaaki; Takita, Masahiro; Kitai, Satoshi; Yada, Norihisa; Hagiwara, Satoru; Inoue, Tatsuo; Minami, Yasunori; Ueshima, Kazuomi; Sakurai, Toshiharu; Kudo, Masatoshi

Nishida, Naoshi; Chishina, Hirokazu; Arizumi, Tadaaki; Takita, Masahiro; Kitai, Satoshi; Yada, Norihisa; Hagiwara, Satoru; Inoue, Tatsuo; Minami, Yasunori; Ueshima, Kazuomi; Sakurai, Toshiharu; Kudo, Masatoshi.

Affiliation

Nishida N; Department of Gastroenterology and Hepatology, Kinki University Faculty of Medicine, Osaka-Sayama, Japan.

Dig Dis ; 32(6): 740-6, 2014.

Article in En | MEDLINE | ID: mdl-25376292

Subject(s)

Azacitidine/analogs & derivatives; Gene Expression Profiling/methods; Gene Expression Regulation, Neoplastic/drug effects; Gene Silencing; Hydroxamic Acids/pharmacology; Aged; Azacitidine/pharmacology; Biopsy, Needle; Carcinoma, Hepatocellular/drug therapy; Carcinoma, Hepatocellular/genetics; Case-Control Studies; DNA Methylation; Decitabine; Epigenesis, Genetic; Female; Humans; Liver Neoplasms/drug therapy; Liver Neoplasms/genetics; Male; Middle Aged; Reference Values; Sampling Studies; Tumor Cells, Cultured/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Azacitidine / Gene Expression Regulation, Neoplastic / Gene Expression Profiling / Gene Silencing / Hydroxamic Acids Type of study: Diagnostic_studies / Observational_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Dig Dis Journal subject: GASTROENTEROLOGIA Year: 2014 Document type: Article Affiliation country: Japan

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