Human SLC4A11-C functions as a DIDS-stimulatable Hâº(OHâ») permeation pathway: partial correction of R109H mutant transport.

Kao, Liyo; Azimov, Rustam; Abuladze, Natalia; Newman, Debra; Kurtz, Ira

Human SLC4A11-C functions as a DIDS-stimulatable Hâº(OHâ») permeation pathway: partial correction of R109H mutant transport.

Kao, Liyo; Azimov, Rustam; Abuladze, Natalia; Newman, Debra; Kurtz, Ira.

Affiliation

Kao L; Division of Nephrology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California; and.
Azimov R; Division of Nephrology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California; and.
Abuladze N; Division of Nephrology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California; and.
Newman D; Division of Nephrology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California; and.
Kurtz I; Division of Nephrology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California; and Brain Research Institute, University of California Los Angeles, Los Angeles, California ikurtz@mednet.ucla.edu.

Am J Physiol Cell Physiol ; 308(2): C176-88, 2015 Jan 15.

Article in En | MEDLINE | ID: mdl-25394471

Subject(s)

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid/pharmacology; Anion Transport Proteins/metabolism; Antiporters/metabolism; Hydroxides/metabolism; Permeability/drug effects; Signal Transduction/drug effects; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid/analogs & derivatives; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid/analogs & derivatives; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid/pharmacology; Anion Transport Proteins/genetics; Antiporters/genetics; Biological Transport/physiology; Cell Line; Cornea/drug effects; Cornea/metabolism; Endothelial Cells/drug effects; Endothelial Cells/metabolism; HEK293 Cells; Humans; Mutation/genetics; RNA, Messenger/genetics

Key words

CHED2; DIDS; cornea; endothelial cell; proton; transport

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Permeability / Signal Transduction / 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid / Antiporters / Anion Transport Proteins / Hydroxides Limits: Humans Language: En Journal: Am J Physiol Cell Physiol Journal subject: FISIOLOGIA Year: 2015 Document type: Article Country of publication: United States

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