Emergence agitation after orthognathic surgery: a randomised controlled comparison between sevoflurane and desflurane.
Acta Anaesthesiol Scand
; 59(2): 224-31, 2015 Feb.
Article
in En
| MEDLINE
| ID: mdl-25395384
ABSTRACT
BACKGROUND:
This study aimed to compare emergence agitation following sevoflurane and desflurane anaesthesia in adults undergoing orthognathic surgery. The hypothesis was that there might be a difference in the incidence of emergence agitation following sevoflurane and desflurane anaesthesia considering the difference in blood solubility and speed of recovery between the two.METHODS:
In this prospective randomised double-blind study, 144 adults undergoing orthognathic surgery were randomly allocated to either sevoflurane or desflurane anaesthesia. The incidence of emergence agitation and possible causative factors were then compared between the groups.RESULTS:
The incidence of emergence agitation was lower in the desflurane group than in the sevoflurane group (24% vs. 71%, P < 0.001). In addition, the time intervals between the discontinuation of anaesthetics and the first response, extubation, and discharge from post-anaesthesia care unit were significantly shorter in the desflurane group (P = 0.002, P < 0.001 and P = 0.003, respectively). The other variables were similar in the two groups.CONCLUSIONS:
In adults undergoing orthognathic surgery, desflurane anaesthesia was associated with less emergence agitation than was sevoflurane anaesthesia.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Psychomotor Agitation
/
Anesthesia Recovery Period
/
Anesthetics, Inhalation
/
Orthognathic Surgery
/
Isoflurane
/
Methyl Ethers
Type of study:
Clinical_trials
/
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
En
Journal:
Acta Anaesthesiol Scand
Year:
2015
Document type:
Article