Pharmacokinetics of doripenem during high volume hemodiafiltration in patients with septic shock.

Tamme, Kadri; Oselin, Kersti; Kipper, Karin; Low, Kaywei; Standing, Joseph F; Metsvaht, Tuuli; Karjagin, Juri; Herodes, Koit; Kern, Hartmut; Starkopf, Joel

Tamme, Kadri; Oselin, Kersti; Kipper, Karin; Low, Kaywei; Standing, Joseph F; Metsvaht, Tuuli; Karjagin, Juri; Herodes, Koit; Kern, Hartmut; Starkopf, Joel.

Affiliation

Tamme K; Clinic of Anaesthesiology and Intensive Care, Tartu University Hospital, Tartu, Estonia; Department of Anaesthesiology and Intensive Care, University of Tartu, Tartu, Estonia.

J Clin Pharmacol ; 55(4): 438-46, 2015 Apr.

Article in En | MEDLINE | ID: mdl-25408310

Subject(s)

Anti-Bacterial Agents/pharmacokinetics; Carbapenems/pharmacokinetics; Hemodiafiltration; Shock, Septic/blood; Shock, Septic/therapy; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents/administration & dosage; Anti-Bacterial Agents/adverse effects; Carbapenems/administration & dosage; Carbapenems/adverse effects; Doripenem; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Monte Carlo Method; Shock, Septic/drug therapy

Key words

antibiotics; carbapenems; dosing; intensive care; renal replacement therapy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Shock, Septic / Carbapenems / Hemodiafiltration / Anti-Bacterial Agents Type of study: Health_economic_evaluation Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: J Clin Pharmacol Year: 2015 Document type: Article Affiliation country: Estonia Country of publication: United kingdom

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