Peritoneal cavity is a route for gut-derived microbial signals to promote autoimmunity in non-obese diabetic mice.

Emani, R; Alam, C; Pekkala, S; Zafar, S; Emani, M R; Hänninen, A

Emani, R; Alam, C; Pekkala, S; Zafar, S; Emani, M R; Hänninen, A.

Affiliation

Emani R; Department of Medical Microbiology and Immunology, University of Turku, Turku, Finland.

Scand J Immunol ; 81(2): 102-9, 2015 Feb.

Article in En | MEDLINE | ID: mdl-25410403

Subject(s)

Autoimmunity/immunology; Intestines/immunology; Microbiota/immunology; Peritoneal Cavity/physiology; Signal Transduction/immunology; Animals; Antigens, CD/immunology; Antigens, CD/metabolism; Antigens, Differentiation, T-Lymphocyte/immunology; Antigens, Differentiation, T-Lymphocyte/metabolism; Blotting, Western; Cells, Cultured; Flow Cytometry; Injections, Intraperitoneal; Interleukin-1 Receptor-Associated Kinases/immunology; Interleukin-1 Receptor-Associated Kinases/metabolism; Intestinal Mucosa/metabolism; Lectins, C-Type/immunology; Lectins, C-Type/metabolism; Lipopolysaccharides/immunology; Lipopolysaccharides/pharmacology; Macrophages, Peritoneal/drug effects; Macrophages, Peritoneal/immunology; Macrophages, Peritoneal/metabolism; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred NOD; Peritoneal Cavity/cytology; Peritoneal Cavity/microbiology; Species Specificity; T-Lymphocytes/drug effects; T-Lymphocytes/immunology; T-Lymphocytes/metabolism; Tumor Necrosis Factor-alpha/immunology; Tumor Necrosis Factor-alpha/metabolism; Weaning

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peritoneal Cavity / Signal Transduction / Autoimmunity / Microbiota / Intestines Language: En Journal: Scand J Immunol Year: 2015 Document type: Article Affiliation country: Finland

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