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Stealing VEGF from thy neighbor.
Domigan, Courtney K; Iruela-Arispe, M Luisa.
Affiliation
  • Domigan CK; Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, 615 Charles E. Young Drive South, Los Angeles, CA 90095, USA.
  • Iruela-Arispe ML; Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, 615 Charles E. Young Drive South, Los Angeles, CA 90095, USA. Electronic address: arispe@mcdb.ucla.edu.
Cell ; 159(3): 473-4, 2014 Oct 23.
Article in En | MEDLINE | ID: mdl-25417099
ABSTRACT
The distribution and patterning of blood vessels is controlled by vascular endothelial growth factor (VEGF), which is precisely regulated throughout its life cycle. Okabe et al. show that VEGF is titrated away from the endothelium by adjacent neurons via endocytosis, regulating density and trajectory of blood vessels.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Retina / Neovascularization, Physiologic / Vascular Endothelial Growth Factor A / Neurons Limits: Animals Language: En Journal: Cell Year: 2014 Document type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Retina / Neovascularization, Physiologic / Vascular Endothelial Growth Factor A / Neurons Limits: Animals Language: En Journal: Cell Year: 2014 Document type: Article Affiliation country: United States