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LRRK2 localizes to endosomes and interacts with clathrin-light chains to limit Rac1 activation.
Schreij, Andrea M A; Chaineau, Mathilde; Ruan, Wenjing; Lin, Susan; Barker, Philip A; Fon, Edward A; McPherson, Peter S.
Affiliation
  • Schreij AM; Department of Neurology and Neurosurgery and McGill Parkinson Program, Montreal Neurological Institute McGill University, Montreal, Quebec, Canada.
  • Chaineau M; Department of Neurology and Neurosurgery and McGill Parkinson Program, Montreal Neurological Institute McGill University, Montreal, Quebec, Canada.
  • Ruan W; Department of Neurology and Neurosurgery and McGill Parkinson Program, Montreal Neurological Institute McGill University, Montreal, Quebec, Canada.
  • Lin S; Department of Neurology and Neurosurgery and McGill Parkinson Program, Montreal Neurological Institute McGill University, Montreal, Quebec, Canada.
  • Barker PA; Department of Neurology and Neurosurgery and McGill Parkinson Program, Montreal Neurological Institute McGill University, Montreal, Quebec, Canada.
  • Fon EA; Department of Neurology and Neurosurgery and McGill Parkinson Program, Montreal Neurological Institute McGill University, Montreal, Quebec, Canada ted.fon@mcgill.ca peter.mcpherson@mcgill.ca.
  • McPherson PS; Department of Neurology and Neurosurgery and McGill Parkinson Program, Montreal Neurological Institute McGill University, Montreal, Quebec, Canada ted.fon@mcgill.ca peter.mcpherson@mcgill.ca.
EMBO Rep ; 16(1): 79-86, 2015 Jan.
Article in En | MEDLINE | ID: mdl-25427558
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endosomes / Protein Serine-Threonine Kinases / Rac1 GTP-Binding Protein / Clathrin Light Chains Limits: Animals / Humans Language: En Journal: EMBO Rep Journal subject: BIOLOGIA MOLECULAR Year: 2015 Document type: Article Affiliation country: Canada Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endosomes / Protein Serine-Threonine Kinases / Rac1 GTP-Binding Protein / Clathrin Light Chains Limits: Animals / Humans Language: En Journal: EMBO Rep Journal subject: BIOLOGIA MOLECULAR Year: 2015 Document type: Article Affiliation country: Canada Country of publication: United kingdom