Prefrontal cortical gamma-aminobutyric acid transmission and cognitive function: drawing links to schizophrenia from preclinical research.

Tse, Maric T; Piantadosi, Patrick T; Floresco, Stan B

Tse, Maric T; Piantadosi, Patrick T; Floresco, Stan B.

Affiliation

Tse MT; Department of Psychology and Brain Research Centre, University of British Columbia, Vancouver, British Columbia, Canada.
Piantadosi PT; Department of Psychology and Brain Research Centre, University of British Columbia, Vancouver, British Columbia, Canada.
Floresco SB; Department of Psychology and Brain Research Centre, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address: floresco@psych.ubc.ca.

Biol Psychiatry ; 77(11): 929-39, 2015 Jun 01.

Article in En | MEDLINE | ID: mdl-25442792

Subject(s)

Cognition Disorders/etiology; Prefrontal Cortex/metabolism; Schizophrenia/complications; Schizophrenia/pathology; Signal Transduction/physiology; Synaptic Transmission/physiology; gamma-Aminobutyric Acid/metabolism; Animals; Humans

Key words

Animal models; Attention; Cognitive deficits; Cognitive flexibility; GABA; Prefrontal cortex; Schizophrenia; Working memory

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Schizophrenia / Signal Transduction / Prefrontal Cortex / Cognition Disorders / Synaptic Transmission / Gamma-Aminobutyric Acid Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Biol Psychiatry Year: 2015 Document type: Article Affiliation country: Canada

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