Invivo absorption behaviour of theophylline from starch-methyl methacrylate matrix tablets in beagle dogs.

Fernández-Campos, F; Ferrero, C; Colom, H; Jiménez-Castellanos, M R

Fernández-Campos, F; Ferrero, C; Colom, H; Jiménez-Castellanos, M R.

Affiliation

Fernández-Campos F; Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain.
Ferrero C; Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Seville, Sevilla, Spain. Electronic address: cferrero@us.es.
Colom H; Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain.
Jiménez-Castellanos MR; Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Seville, Sevilla, Spain.

Int J Pharm ; 478(2): 684-92, 2015 Jan 30.

Article in En | MEDLINE | ID: mdl-25476254

Subject(s)

Methylmethacrylate/chemistry; Starch/chemistry; Theophylline/pharmacokinetics; Animals; Biological Availability; Delayed-Action Preparations/administration & dosage; Delayed-Action Preparations/chemistry; Delayed-Action Preparations/pharmacokinetics; Dogs; Fasting/metabolism; Female; Models, Biological; Tablets; Theophylline/administration & dosage; Theophylline/blood; Theophylline/chemistry

Key words

Anhydrous theophylline; Beagle dog; IVIVC; Pharmacokinetics; Potato starch-methyl methacrylate copolymers; Sustained-release matrix tablet

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Starch / Theophylline / Methylmethacrylate Type of study: Prognostic_studies Limits: Animals Language: En Journal: Int J Pharm Year: 2015 Document type: Article Affiliation country: Spain Country of publication: Netherlands

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