Sex hormone modulation of both induction and inhibition of CYP1A by genistein in HepG2/C3A cells.

Liu, Yitong; Santillo, Michael F; Flynn, Thomas J; Ferguson, Martine S

Liu, Yitong; Santillo, Michael F; Flynn, Thomas J; Ferguson, Martine S.

Affiliation

Liu Y; Division of Toxicology, Office of Applied Research and Safety Assessment, Center for Food Safety and Applied Nutrition, US Food and Drug Administration, Laurel, MD, USA, yitong.liu@fda.hhs.gov.

In Vitro Cell Dev Biol Anim ; 51(4): 426-31, 2015 Apr.

Article in En | MEDLINE | ID: mdl-25479735

Subject(s)

Aryl Hydrocarbon Hydroxylases/antagonists & inhibitors; Genistein/pharmacology; Gonadal Steroid Hormones/pharmacology; Aryl Hydrocarbon Hydroxylases/metabolism; Benzoflavones/pharmacology; Cytochrome P-450 CYP1A1/genetics; Cytochrome P-450 CYP1A2/genetics; Female; Gene Expression Regulation, Enzymologic/drug effects; Hep G2 Cells/drug effects; Humans; Male; Testosterone/pharmacology; beta-Naphthoflavone/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gonadal Steroid Hormones / Aryl Hydrocarbon Hydroxylases / Genistein Limits: Female / Humans / Male Language: En Journal: In Vitro Cell Dev Biol Anim Journal subject: BIOLOGIA Year: 2015 Document type: Article

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