Antibodies, Bacterial/blood; Drug Carriers/therapeutic use; Escherichia coli Infections/prevention & control; Escherichia coli/immunology; Polysaccharides, Bacterial/immunology; Vaccines, Conjugate/immunology; Animals; Antibodies, Bacterial/immunology; Bacterial Adhesion/immunology; Bacterial Toxins/chemistry; Bacterial Toxins/immunology; Cell Line; Cytochromes c/chemistry; Cytochromes c/immunology; Endotoxins/immunology; Enterotoxins/chemistry; Enterotoxins/immunology; Escherichia coli/classification; Escherichia coli Infections/immunology; Escherichia coli Infections/microbiology; Escherichia coli Proteins/chemistry; Escherichia coli Proteins/immunology; Female; Hemolytic-Uremic Syndrome/immunology; Hemolytic-Uremic Syndrome/microbiology; Hemolytic-Uremic Syndrome/prevention & control; Humans; Male; Mice; Mice, Inbred BALB C; Nanoparticles/therapeutic use; Rabbits; Silicon Dioxide/chemistry; Vaccines, Conjugate/therapeutic use

CT, cholera toxin; E. coli; E. coli, Escherichia coli; EAEC, enteroaggregative E. coli; EHEC, enterohemorrhagic E. coli; EPEC, enteropathogenic E. coli; EtxB, non-toxic B subunit of LT; HUS, hemolytic uremic syndrome; LPS, lipopolysaccharide; LT, heat labile toxin of ETEC; O111 polysaccharide; PAGE, polyacrylamide gel electrophoresis; SBA-15, Santa Barbara Amorphous-15; SDS, sodium dodecyl sulfate; STEC, shiga-producing toxins E. coli; aEPEC, atypical EPEC; conjugated vaccine; t-EPEC, typical EPEC