Proteasome inhibitors suppress the protein expression of mutant p53.

Halasi, Marianna; Pandit, Bulbul; Gartel, Andrei L

Halasi, Marianna; Pandit, Bulbul; Gartel, Andrei L.

Affiliation

Halasi M; a Department of Medicine ; University of Illinois at Chicago ; Chicago , IL USA.

Cell Cycle ; 13(20): 3202-6, 2014.

Article in En | MEDLINE | ID: mdl-25485499

Subject(s)

Proteasome Inhibitors/pharmacology; Proto-Oncogene Proteins c-mdm2/metabolism; Tumor Suppressor Protein p53/metabolism; Arsenic Trioxide; Arsenicals/pharmacology; Cell Line, Tumor; Humans; Oxides/pharmacology; Proto-Oncogene Proteins c-mdm2/genetics; RNA Interference; Tumor Suppressor Protein p53/genetics

Key words

Arsenic trioxide; Bax, Bcl-2-associated X; Bcl-2, B-cell lymphoma 2; FOXM1, Forkhead Box M1, Mcl-1, Myeloid cell leukemia sequence 1; HDM2; HDM2, human double minute 2; PUMA, p53 upregulated modulator of apoptosis; RNAi; p53; proteasome inhibitors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tumor Suppressor Protein p53 / Proto-Oncogene Proteins c-mdm2 / Proteasome Inhibitors Limits: Humans Language: En Journal: Cell Cycle Year: 2014 Document type: Article Country of publication: United States

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