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Functional impact of integrin α5ß1 on the homeostasis of intervertebral discs: a study of mechanotransduction pathways using a novel dynamic loading organ culture system.
Kurakawa, Takuto; Kakutani, Kenichiro; Morita, Yusuke; Kato, Yuki; Yurube, Takashi; Hirata, Hiroaki; Miyazaki, Shingo; Terashima, Yoshiki; Maeno, Koichiro; Takada, Toru; Doita, Minoru; Kurosaka, Masahiro; Inoue, Nozomu; Masuda, Koichi; Nishida, Kotaro.
Affiliation
  • Kurakawa T; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo Prefecture 657-8501, Japan.
  • Kakutani K; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo Prefecture 657-8501, Japan. Electronic address: kenkakutani@gmail.com.
  • Morita Y; Department of Biomedical Engineering, Doshisha University, Karasuma-Higashi-iru, Kyoto, Kyoto Prefecture 602-8580, Japan.
  • Kato Y; Department of Biomedical Engineering, Doshisha University, Karasuma-Higashi-iru, Kyoto, Kyoto Prefecture 602-8580, Japan.
  • Yurube T; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo Prefecture 657-8501, Japan.
  • Hirata H; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo Prefecture 657-8501, Japan.
  • Miyazaki S; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo Prefecture 657-8501, Japan.
  • Terashima Y; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo Prefecture 657-8501, Japan.
  • Maeno K; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo Prefecture 657-8501, Japan.
  • Takada T; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo Prefecture 657-8501, Japan.
  • Doita M; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo Prefecture 657-8501, Japan.
  • Kurosaka M; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo Prefecture 657-8501, Japan.
  • Inoue N; Department of Biomedical Engineering, Doshisha University, Karasuma-Higashi-iru, Kyoto, Kyoto Prefecture 602-8580, Japan; Department of Orthopedic Surgery, Rush University Medical Center, 1653 W. Congress Parkway, Chicago, IL 60612, USA.
  • Masuda K; Department of Orthopaedic Surgery, University of California San Diego School of Medicine, 9500 Gilman Drive, La Jolla, San Diego, CA 92093, USA.
  • Nishida K; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo Prefecture 657-8501, Japan.
Spine J ; 15(3): 417-26, 2015 Mar 01.
Article in En | MEDLINE | ID: mdl-25546513
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organ Culture Techniques / Matrix Metalloproteinase 3 / Integrin alpha5beta1 / Mechanotransduction, Cellular / Intervertebral Disc Degeneration / Intervertebral Disc Limits: Animals Language: En Journal: Spine J Journal subject: ORTOPEDIA Year: 2015 Document type: Article Affiliation country: Japan Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organ Culture Techniques / Matrix Metalloproteinase 3 / Integrin alpha5beta1 / Mechanotransduction, Cellular / Intervertebral Disc Degeneration / Intervertebral Disc Limits: Animals Language: En Journal: Spine J Journal subject: ORTOPEDIA Year: 2015 Document type: Article Affiliation country: Japan Country of publication: United States