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Cutting edge: epigenetic regulation of Foxp3 defines a stable population of CD4+ regulatory T cells in tumors from mice and humans.
Waight, Jeremy D; Takai, Shinji; Marelli, Bo; Qin, Guozhong; Hance, Kenneth W; Zhang, Dong; Tighe, Robert; Lan, Yan; Lo, Kin-Ming; Sabzevari, Helen; Hofmeister, Robert; Wilson, Nicholas S.
Affiliation
  • Waight JD; Immuno-Oncology Platform, EMD Serono Research and Development Institute, Billerica, MA 01821;
  • Takai S; Oncology Section, Medical Affairs, Ono Pharmaceutical Co., Ltd., Osaka 541-8564, Japan;
  • Marelli B; Immuno-Oncology Platform, EMD Serono Research and Development Institute, Billerica, MA 01821;
  • Qin G; Immuno-Oncology Platform, EMD Serono Research and Development Institute, Billerica, MA 01821;
  • Hance KW; Immuno-Oncology Platform, EMD Serono Research and Development Institute, Billerica, MA 01821;
  • Zhang D; Immuno-Oncology Platform, EMD Serono Research and Development Institute, Billerica, MA 01821;
  • Tighe R; Immuno-Oncology Platform, EMD Serono Research and Development Institute, Billerica, MA 01821;
  • Lan Y; Immuno-Oncology Platform, EMD Serono Research and Development Institute, Billerica, MA 01821;
  • Lo KM; Immuno-Oncology Platform, EMD Serono Research and Development Institute, Billerica, MA 01821;
  • Sabzevari H; Immuno-Oncology Platform, EMD Serono Research and Development Institute, Billerica, MA 01821;
  • Hofmeister R; Immuno-Oncology Platform, EMD Serono Research and Development Institute, Billerica, MA 01821; Robert.Hofmeister@EMDSerono.com.
  • Wilson NS; Immuno-Oncology Platform, EMD Serono Research and Development Institute, Billerica, MA 01821; Now Cancer Immunology Group, Agenus, Lexington, MA 02421.
J Immunol ; 194(3): 878-82, 2015 Feb 01.
Article in En | MEDLINE | ID: mdl-25548231

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation, Neoplastic / T-Lymphocytes, Regulatory / Epigenesis, Genetic / Forkhead Transcription Factors / Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Immunol Year: 2015 Document type: Article Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation, Neoplastic / T-Lymphocytes, Regulatory / Epigenesis, Genetic / Forkhead Transcription Factors / Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Immunol Year: 2015 Document type: Article Country of publication: United States