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Paclitaxel resistance increases oncolytic adenovirus efficacy via upregulated CAR expression and dysfunctional cell cycle control.
Ingemarsdotter, Carin K; Tookman, Laura A; Browne, Ashley; Pirlo, Katrina; Cutts, Rosalind; Chelela, Claude; Khurrum, Karisma F; Leung, Elaine Y L; Dowson, Suzanne; Webber, Lee; Khan, Iftekhar; Ennis, Darren; Syed, Nelofer; Crook, Tim R; Brenton, James D; Lockley, Michelle; McNeish, Iain A.
Affiliation
  • Ingemarsdotter CK; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
  • Tookman LA; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
  • Browne A; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
  • Pirlo K; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
  • Cutts R; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
  • Chelela C; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
  • Khurrum KF; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
  • Leung EY; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.
  • Dowson S; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.
  • Webber L; Cancer Research UK and UCL Clinical Trials Centre, London, UK.
  • Khan I; Cancer Research UK and UCL Clinical Trials Centre, London, UK.
  • Ennis D; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.
  • Syed N; Division of Brain Sciences, Faculty of Medicine, Imperial College, London, UK.
  • Crook TR; Dundee Cancer Centre, University of Dundee, Ninewells Hospital, Dundee, UK.
  • Brenton JD; Cancer Research UK Cambridge Institute, Cambridge, UK.
  • Lockley M; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
  • McNeish IA; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK. Electronic address: iain.mcneish@glasgow.ac.uk.
Mol Oncol ; 9(4): 791-805, 2015 Apr.
Article in En | MEDLINE | ID: mdl-25560085
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Up-Regulation / Adenoviridae / Paclitaxel / Drug Resistance, Neoplasm / Oncolytic Viruses / Cell Cycle Checkpoints / Coxsackie and Adenovirus Receptor-Like Membrane Protein Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Mol Oncol Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2015 Document type: Article Affiliation country: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Up-Regulation / Adenoviridae / Paclitaxel / Drug Resistance, Neoplasm / Oncolytic Viruses / Cell Cycle Checkpoints / Coxsackie and Adenovirus Receptor-Like Membrane Protein Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Mol Oncol Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2015 Document type: Article Affiliation country: United kingdom