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Stability of proICA512/IA-2 and its targeting to insulin secretory granules require ß4-sheet-mediated dimerization of its ectodomain in the endoplasmic reticulum.
Torkko, Juha M; Primo, M Evangelina; Dirkx, Ronald; Friedrich, Anne; Viehrig, Antje; Vergari, Elisa; Borgonovo, Barbara; Sönmez, Anke; Wegbrod, Carolin; Lachnit, Martina; Münster, Carla; Sica, Mauricio P; Ermácora, Mario R; Solimena, Michele.
Affiliation
  • Torkko JM; Paul Langerhans Institute Dresden, Uniklinikum Carl Gustav Carus, TU Dresden, Germany German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.
  • Primo ME; University of Buenos Aires, Buenos Aires, Argentina Instituto Multidisciplinario de Biología Celular, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina.
  • Dirkx R; Paul Langerhans Institute Dresden, Uniklinikum Carl Gustav Carus, TU Dresden, Germany German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.
  • Friedrich A; Paul Langerhans Institute Dresden, Uniklinikum Carl Gustav Carus, TU Dresden, Germany German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.
  • Viehrig A; Paul Langerhans Institute Dresden, Uniklinikum Carl Gustav Carus, TU Dresden, Germany German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.
  • Vergari E; Paul Langerhans Institute Dresden, Uniklinikum Carl Gustav Carus, TU Dresden, Germany German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.
  • Borgonovo B; Paul Langerhans Institute Dresden, Uniklinikum Carl Gustav Carus, TU Dresden, Germany Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
  • Sönmez A; Paul Langerhans Institute Dresden, Uniklinikum Carl Gustav Carus, TU Dresden, Germany German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.
  • Wegbrod C; Paul Langerhans Institute Dresden, Uniklinikum Carl Gustav Carus, TU Dresden, Germany German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.
  • Lachnit M; Paul Langerhans Institute Dresden, Uniklinikum Carl Gustav Carus, TU Dresden, Germany German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.
  • Münster C; Paul Langerhans Institute Dresden, Uniklinikum Carl Gustav Carus, TU Dresden, Germany German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.
  • Sica MP; Instituto Multidisciplinario de Biología Celular, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina Departamento de Ciencia y Tecnología, Universidad Nacional de Quilmes, Bernal, Buenos Aires, Argentina.
  • Ermácora MR; Instituto Multidisciplinario de Biología Celular, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina Departamento de Ciencia y Tecnología, Universidad Nacional de Quilmes, Bernal, Buenos Aires, Argentina.
  • Solimena M; Paul Langerhans Institute Dresden, Uniklinikum Carl Gustav Carus, TU Dresden, Germany German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany michele.solimena@tu-dresden.de.
Mol Cell Biol ; 35(6): 914-27, 2015 Mar.
Article in En | MEDLINE | ID: mdl-25561468
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Secretory Vesicles / Cytoplasmic Granules / Endoplasmic Reticulum / Receptor-Like Protein Tyrosine Phosphatases, Class 8 / Insulin Limits: Animals Language: En Journal: Mol Cell Biol Year: 2015 Document type: Article Affiliation country: Germany Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Secretory Vesicles / Cytoplasmic Granules / Endoplasmic Reticulum / Receptor-Like Protein Tyrosine Phosphatases, Class 8 / Insulin Limits: Animals Language: En Journal: Mol Cell Biol Year: 2015 Document type: Article Affiliation country: Germany Country of publication: United States