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Faster in vivo clearance of human embryonic kidney than Chinese hamster ovary cell derived protein: Role of glycan mediated clearance.
Wang, Mengmeng; Ishino, Tetsuya; Joyce, Alison; Tam, Amy; Duan, Weili; Lin, Laura; Somers, William S; Kriz, Ronald; O'Hara, Denise M.
Affiliation
  • Wang M; Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer Inc., Andover, MA 01810, USA. Electronic address: Mengmeng.Wang@pfizer.com.
  • Ishino T; Department of Global Biotherapeutics Technologies, Pfizer Inc., Cambridge, MA 02140, USA.
  • Joyce A; Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer Inc., Andover, MA 01810, USA.
  • Tam A; Department of Global Biotherapeutics Technologies, Pfizer Inc., Cambridge, MA 02140, USA.
  • Duan W; Department of Global Biotherapeutics Technologies, Pfizer Inc., Cambridge, MA 02140, USA.
  • Lin L; Department of Global Biotherapeutics Technologies, Pfizer Inc., Cambridge, MA 02140, USA.
  • Somers WS; Department of Global Biotherapeutics Technologies, Pfizer Inc., Cambridge, MA 02140, USA.
  • Kriz R; Department of Global Biotherapeutics Technologies, Pfizer Inc., Cambridge, MA 02140, USA.
  • O'Hara DM; Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer Inc., Andover, MA 01810, USA.
J Biosci Bioeng ; 119(6): 657-60, 2015 Jun.
Article in En | MEDLINE | ID: mdl-25575972

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glycosylation / Mannans / Antibodies Limits: Animals / Humans Language: En Journal: J Biosci Bioeng Journal subject: ENGENHARIA BIOMEDICA / MICROBIOLOGIA Year: 2015 Document type: Article Country of publication: Japan

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glycosylation / Mannans / Antibodies Limits: Animals / Humans Language: En Journal: J Biosci Bioeng Journal subject: ENGENHARIA BIOMEDICA / MICROBIOLOGIA Year: 2015 Document type: Article Country of publication: Japan