Conquering rotavirus: from discovery to global vaccine implementation.
J Paediatr Child Health
; 51(1): 34-9, 2015 Jan.
Article
in En
| MEDLINE
| ID: mdl-25586843
ABSTRACT
Rotavirus, the commonest cause of severe dehydrating gastroenteritis world-wide, was discovered less than 50 years ago. It causes about 450,000 deaths per year in children <5 years of age and hospitalises millions more. Rotavirus vaccines have been shown to have a major impact on hospital admissions due to rotavirus gastroenteritis and all-cause gastroenteritis and reduce mortality in developing countries. In Australia, there has been a 71% decrease in rotavirus hospitalisations in children 0-5 years of age. From the discovery of rotavirus as the major causative agent for severe gastroenteritis, through vaccine development and vaccine post-marketing surveillance activities, Australian scientists and clinicians have played a significant role in the global effort to reduce the burden of rotavirus infection.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Rotavirus Infections
/
Rotavirus Vaccines
/
Gastroenteritis
Limits:
Child, preschool
/
Humans
/
Infant
Country/Region as subject:
Oceania
Language:
En
Journal:
J Paediatr Child Health
Journal subject:
PEDIATRIA
Year:
2015
Document type:
Article
Affiliation country:
Australia
Country of publication:
AU
/
AUSTRALIA
/
AUSTRÁLIA