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Hypoxia enhances migration and invasion in glioblastoma by promoting a mesenchymal shift mediated by the HIF1α-ZEB1 axis.
Joseph, Justin V; Conroy, Siobhan; Pavlov, Kirill; Sontakke, Pallavi; Tomar, Tushar; Eggens-Meijer, Ellie; Balasubramaniyan, Veerakumar; Wagemakers, Michiel; den Dunnen, Wilfred F A; Kruyt, Frank A E.
Affiliation
  • Joseph JV; Department of Medical Oncology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
  • Conroy S; Department of Pathology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
  • Pavlov K; Department of Medical Oncology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
  • Sontakke P; Department of Experimental Hematology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
  • Tomar T; Department of Gynecologic Oncology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
  • Eggens-Meijer E; Department of Neuroscience, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
  • Balasubramaniyan V; Department of Neuroscience, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
  • Wagemakers M; Department of Neuro-surgery, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
  • den Dunnen WF; Department of Pathology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
  • Kruyt FA; Department of Medical Oncology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. Electronic address: f.a.e.kruyt@umcg.nl.
Cancer Lett ; 359(1): 107-16, 2015 Apr 01.
Article in En | MEDLINE | ID: mdl-25592037
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Brain Neoplasms / Cell Movement / Glioblastoma / Homeodomain Proteins / Hypoxia-Inducible Factor 1, alpha Subunit / Epithelial-Mesenchymal Transition Type of study: Prognostic_studies Limits: Humans Language: En Journal: Cancer Lett Year: 2015 Document type: Article Affiliation country: Netherlands Country of publication: Ireland
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Brain Neoplasms / Cell Movement / Glioblastoma / Homeodomain Proteins / Hypoxia-Inducible Factor 1, alpha Subunit / Epithelial-Mesenchymal Transition Type of study: Prognostic_studies Limits: Humans Language: En Journal: Cancer Lett Year: 2015 Document type: Article Affiliation country: Netherlands Country of publication: Ireland