Identification and isolation of medicarpin and a substituted benzofuran as potent leukotriene inhibitors in an anti-inflammatory Chinese herb.

Miller, D K; Sadowski, S; Han, G Q; Joshua, H

Miller, D K; Sadowski, S; Han, G Q; Joshua, H.

Affiliation

Miller DK; Department of Biochemistry, Merck Sharp & Dohme Research Laboratories, Rahway, NJ 07065.

Prostaglandins Leukot Essent Fatty Acids ; 38(2): 137-43, 1989 Nov.

Article in En | MEDLINE | ID: mdl-2559412

Subject(s)

Anti-Inflammatory Agents, Non-Steroidal/isolation & purification; Benzofurans/isolation & purification; Drugs, Chinese Herbal/isolation & purification; Leukotriene Antagonists; Plants, Medicinal/analysis; Pterocarpans; Animals; Anti-Inflammatory Agents, Non-Steroidal/pharmacology; Benzofurans/pharmacology; Benzopyrans/pharmacology; Cells, Cultured; Chromatography, Gel; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal/pharmacology; Female; Leukotriene B4/biosynthesis; Lipoxygenase Inhibitors; Mice

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Collection: 01-internacional Database: MEDLINE Main subject: Plants, Medicinal / Benzofurans / Drugs, Chinese Herbal / Anti-Inflammatory Agents, Non-Steroidal / Leukotriene Antagonists / Pterocarpans Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Prostaglandins Leukot Essent Fatty Acids Journal subject: ENDOCRINOLOGIA Year: 1989 Document type: Article

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