Secretomes from bone marrow-derived mesenchymal stromal cells enhance periodontal tissue regeneration.

Kawai, Takamasa; Katagiri, Wataru; Osugi, Masashi; Sugimura, Yukiko; Hibi, Hideharu; Ueda, Minoru

Kawai, Takamasa; Katagiri, Wataru; Osugi, Masashi; Sugimura, Yukiko; Hibi, Hideharu; Ueda, Minoru.

Affiliation

Kawai T; Department of Oral and Maxillofacial Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Katagiri W; Department of Oral and Maxillofacial Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan. Electronic address: w-kat@med.nagoya-u.ac.jp.
Osugi M; Department of Oral and Maxillofacial Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Sugimura Y; Department of Oral and Maxillofacial Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Hibi H; Department of Oral and Maxillofacial Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Ueda M; Department of Oral and Maxillofacial Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Cytotherapy ; 17(4): 369-81, 2015 Apr.

Article in En | MEDLINE | ID: mdl-25595330

Subject(s)

Cell- and Tissue-Based Therapy/methods; Guided Tissue Regeneration, Periodontal/methods; Mesenchymal Stem Cells/metabolism; Periodontium/physiology; Regeneration; Animals; Culture Media, Conditioned/pharmacology; Cytokines/metabolism; Hepatocyte Growth Factor/metabolism; Human Umbilical Vein Endothelial Cells; Humans; Insulin-Like Growth Factor I/metabolism; Intercellular Signaling Peptides and Proteins/metabolism; Male; Mesenchymal Stem Cells/cytology; Mesenchymal Stem Cells/drug effects; Neovascularization, Physiologic/drug effects; Neovascularization, Physiologic/physiology; Osteogenesis/drug effects; Periodontium/blood supply; Rats; Rats, Wistar; Transforming Growth Factor beta1/metabolism; Vascular Endothelial Growth Factor A/metabolism

Key words

angiogenesis; conditioned medium; mesenchymal stromal cell; migration; paracrine effects; periodontal regeneration

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Regeneration / Periodontium / Guided Tissue Regeneration, Periodontal / Mesenchymal Stem Cells / Cell- and Tissue-Based Therapy Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Cytotherapy Journal subject: TERAPEUTICA Year: 2015 Document type: Article Affiliation country: Japan Country of publication: United kingdom

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