Effect of nepafenac eye drops on pain associated with pterygium surgery.
Eye Contact Lens
; 41(3): 187-9, 2015 May.
Article
in En
| MEDLINE
| ID: mdl-25603438
ABSTRACT
OBJECTIVE:
To assess the effects of nepafenac ophthalmic suspension 0.1% for control of pain in patients undergoing pterygium surgery.METHODS:
This randomized, double-masked placebo-controlled study included 62 adults undergoing pterygium surgery. Patients were randomly assigned to receive nepafenac ophthalmic suspension 0.1% or balanced salt solution placebo. They were asked to assess the level of pain using an 11-point numeric rating scale at 6, 12, 24, 48, and 72 hr after surgery. Patients also were evaluated daily for the progression of corneal epithelial healing until complete closure was observed.RESULTS:
Except at 72 hr after surgery, the patients reported significantly less pain in eyes receiving nepafenac than in eyes receiving placebo. There was no statistical difference between the two groups in corneal epithelial healing.CONCLUSIONS:
Treatment with nepafenac ophthalmic suspension 0.1% significantly reduced postoperative pain compared with placebo after pterygium surgery.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Ophthalmic Solutions
/
Pain, Postoperative
/
Phenylacetates
/
Pterygium
/
Anti-Inflammatory Agents, Non-Steroidal
/
Benzeneacetamides
Type of study:
Clinical_trials
/
Risk_factors_studies
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Eye Contact Lens
Journal subject:
OFTALMOLOGIA
Year:
2015
Document type:
Article
Affiliation country:
Turkey