Paraxanthine/Caffeine Concentration Ratios in Hair: An Alternative for Plasma-Based Phenotyping of Cytochrome P450 1A2?

De Kesel, Pieter M M; Lambert, Willy E; Stove, Christophe P

De Kesel, Pieter M M; Lambert, Willy E; Stove, Christophe P.

Affiliation

De Kesel PM; Laboratory of Toxicology, Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000, Ghent, Belgium.

Clin Pharmacokinet ; 54(7): 771-81, 2015 Jul.

Article in En | MEDLINE | ID: mdl-25603821

Subject(s)

Caffeine/pharmacokinetics; Cytochrome P-450 CYP1A2/metabolism; Hair/metabolism; Theophylline/pharmacokinetics; Adult; Caffeine/analysis; Caffeine/blood; Cytochrome P-450 CYP1A2/blood; Female; Hair/chemistry; Humans; Male; Middle Aged; Phenotype; Theophylline/analysis; Theophylline/blood; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Theophylline / Caffeine / Cytochrome P-450 CYP1A2 / Hair Type of study: Prognostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Clin Pharmacokinet Year: 2015 Document type: Article Affiliation country: Belgium

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