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Phase I and biomarker study of OPB-51602, a novel signal transducer and activator of transcription (STAT) 3 inhibitor, in patients with refractory solid malignancies.
Wong, A L; Soo, R A; Tan, D S; Lee, S C; Lim, J S; Marban, P C; Kong, L R; Lee, Y J; Wang, L Z; Thuya, W L; Soong, R; Yee, M Q; Chin, T M; Cordero, M T; Asuncion, B R; Pang, B; Pervaiz, S; Hirpara, J L; Sinha, A; Xu, W W; Yuasa, M; Tsunoda, T; Motoyama, M; Yamauchi, T; Goh, B C.
Affiliation
  • Wong AL; Department of Haematology-Oncology, National University Health System; Haematology Oncology Research Group, National University Cancer Institute of Singapore, National University Health System; Cancer Science Institute.
  • Soo RA; Department of Haematology-Oncology, National University Health System; Haematology Oncology Research Group, National University Cancer Institute of Singapore, National University Health System; Cancer Science Institute.
  • Tan DS; Department of Medical Oncology, National Cancer Centre.
  • Lee SC; Department of Haematology-Oncology, National University Health System; Haematology Oncology Research Group, National University Cancer Institute of Singapore, National University Health System; Cancer Science Institute.
  • Lim JS; Department of Haematology-Oncology, National University Health System; Haematology Oncology Research Group, National University Cancer Institute of Singapore, National University Health System.
  • Marban PC; Haematology Oncology Research Group, National University Cancer Institute of Singapore, National University Health System.
  • Kong LR; Cancer Science Institute.
  • Lee YJ; Cancer Science Institute.
  • Wang LZ; Cancer Science Institute; Departments of Pharmacology.
  • Thuya WL; Cancer Science Institute.
  • Soong R; Cancer Science Institute.
  • Yee MQ; Cancer Science Institute.
  • Chin TM; Department of Haematology-Oncology, National University Health System; Haematology Oncology Research Group, National University Cancer Institute of Singapore, National University Health System; Cancer Science Institute.
  • Cordero MT; Haematology Oncology Research Group, National University Cancer Institute of Singapore, National University Health System.
  • Asuncion BR; Cancer Science Institute.
  • Pang B; Cancer Science Institute.
  • Pervaiz S; Physiology, Yong Loo Lin School of Medicine.
  • Hirpara JL; Cancer Science Institute.
  • Sinha A; Department of Diagnostic Imaging, National University Health System, Singapore.
  • Xu WW; Otsuka Beijing Research Institute, Beijing, China.
  • Yuasa M; Otsuka Pharmaceutical Co., Ltd, Chiyoda-ku.
  • Tsunoda T; Otsuka Pharmaceutical Co., Ltd, Chiyoda-ku.
  • Motoyama M; Otsuka Pharmaceutical Co., Ltd, Chiyoda-ku.
  • Yamauchi T; Fuji Memorial Research Institute, Otsuka Pharmaceutical Co. Ltd, Chiyoda-ku, Japan.
  • Goh BC; Department of Haematology-Oncology, National University Health System; Haematology Oncology Research Group, National University Cancer Institute of Singapore, National University Health System; Cancer Science Institute; Departments of Pharmacology. Electronic address: phcgbc@nus.edu.sg.
Ann Oncol ; 26(5): 998-1005, 2015 May.
Article in En | MEDLINE | ID: mdl-25609248
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers, Tumor / Carcinoma, Non-Small-Cell Lung / STAT3 Transcription Factor / Lung Neoplasms / Antineoplastic Agents Type of study: Clinical_trials / Diagnostic_studies / Prognostic_studies Limits: Aged80 Country/Region as subject: Asia Language: En Journal: Ann Oncol Journal subject: NEOPLASIAS Year: 2015 Document type: Article
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers, Tumor / Carcinoma, Non-Small-Cell Lung / STAT3 Transcription Factor / Lung Neoplasms / Antineoplastic Agents Type of study: Clinical_trials / Diagnostic_studies / Prognostic_studies Limits: Aged80 Country/Region as subject: Asia Language: En Journal: Ann Oncol Journal subject: NEOPLASIAS Year: 2015 Document type: Article