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Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: implications for targeting cancer stem cells.
Morgan, R G; Molnár, E; Jones, R F; Collard, T J; Lane, J D; Greenhough, A; Paraskeva, C; Williams, A C.
Affiliation
  • Morgan RG; Cancer Research UK Colorectal Tumour Biology Group, School of Cellular and Molecular Medicine, Bristol BS8 1TD, UK.
  • Molnár E; School of Physiology and Pharmacology, Bristol BS8 1TD, UK.
  • Jones RF; Cancer Research UK Colorectal Tumour Biology Group, School of Cellular and Molecular Medicine, Bristol BS8 1TD, UK.
  • Collard TJ; Cancer Research UK Colorectal Tumour Biology Group, School of Cellular and Molecular Medicine, Bristol BS8 1TD, UK.
  • Lane JD; Cell Biology Laboratories, School of Biochemistry, University of Bristol, Medical Sciences Building, University Walk, Bristol BS8 1TD, UK.
  • Greenhough A; Cancer Research UK Colorectal Tumour Biology Group, School of Cellular and Molecular Medicine, Bristol BS8 1TD, UK.
  • Paraskeva C; Cancer Research UK Colorectal Tumour Biology Group, School of Cellular and Molecular Medicine, Bristol BS8 1TD, UK.
  • Williams AC; Cancer Research UK Colorectal Tumour Biology Group, School of Cellular and Molecular Medicine, Bristol BS8 1TD, UK.
Br J Cancer ; 112(4): 714-9, 2015 Feb 17.
Article in En | MEDLINE | ID: mdl-25611300
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stress, Physiological / Neoplastic Stem Cells / Colorectal Neoplasms / Adenoma / Cell Membrane / Receptors, G-Protein-Coupled / Glucose Limits: Humans Language: En Journal: Br J Cancer Year: 2015 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stress, Physiological / Neoplastic Stem Cells / Colorectal Neoplasms / Adenoma / Cell Membrane / Receptors, G-Protein-Coupled / Glucose Limits: Humans Language: En Journal: Br J Cancer Year: 2015 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom