Hepatitis E virus enters liver cells through a dynamin-2, clathrin and membrane cholesterol-dependent pathway.

Holla, Prasida; Ahmad, Imran; Ahmed, Zulfazal; Jameel, Shahid

Holla, Prasida; Ahmad, Imran; Ahmed, Zulfazal; Jameel, Shahid.

Affiliation

Holla P; Virology Group, International Centre for Genetic Engineering Biotechnology, New Delhi, India.

Traffic ; 16(4): 398-416, 2015 Apr.

Article in En | MEDLINE | ID: mdl-25615268

Subject(s)

Cholesterol/metabolism; Clathrin/metabolism; Dynamin II/metabolism; Hepatitis E virus/physiology; Hepatocytes/virology; Liver/virology; Virus Internalization; Actins/metabolism; Cell Line; Cell Line, Tumor; Escherichia coli/metabolism; HEK293 Cells; HeLa Cells; Hepatocytes/metabolism; Humans; Liver/metabolism; Phosphatidylinositol 3-Kinase/metabolism; Pinocytosis/physiology; Proto-Oncogene Proteins c-akt/metabolism; Signal Transduction/physiology; Virus Replication/physiology

Key words

PI3 kinase; actin; cholesterol; clathrin; dynamin; hepatitis; hepatitis E virus; virus-like particle

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cholesterol / Clathrin / Hepatitis E virus / Hepatocytes / Dynamin II / Virus Internalization / Liver Limits: Humans Language: En Journal: Traffic Journal subject: FISIOLOGIA Year: 2015 Document type: Article Affiliation country: India Country of publication: United kingdom

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