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ST-246 is a key antiviral to inhibit the viral F13L phospholipase, one of the essential proteins for orthopoxvirus wrapping.
Duraffour, Sophie; Lorenzo, María M; Zöller, Gudrun; Topalis, Dimitri; Grosenbach, Doug; Hruby, Dennis E; Andrei, Graciela; Blasco, Rafael; Meyer, Hermann; Snoeck, Robert.
Affiliation
  • Duraffour S; Rega Institute, Laboratory of Virology and Chemotherapy, KU Leuven, Leuven, Belgium sophie.duraffour@rega.kuleuven.be.
  • Lorenzo MM; Departamento de Biotecnología, INIA, Madrid, Spain.
  • Zöller G; Bundeswehr Institute of Microbiology, Munich, Germany.
  • Topalis D; Rega Institute, Laboratory of Virology and Chemotherapy, KU Leuven, Leuven, Belgium.
  • Grosenbach D; SIGA Technologies Inc., Corvallis, OR, USA.
  • Hruby DE; SIGA Technologies Inc., Corvallis, OR, USA.
  • Andrei G; Rega Institute, Laboratory of Virology and Chemotherapy, KU Leuven, Leuven, Belgium.
  • Blasco R; Departamento de Biotecnología, INIA, Madrid, Spain.
  • Meyer H; Bundeswehr Institute of Microbiology, Munich, Germany.
  • Snoeck R; Rega Institute, Laboratory of Virology and Chemotherapy, KU Leuven, Leuven, Belgium.
J Antimicrob Chemother ; 70(5): 1367-80, 2015 May.
Article in En | MEDLINE | ID: mdl-25630650
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Phospholipases / Vaccinia virus / Benzamides / Cowpox virus / Orthopoxvirus / Virus Assembly / Isoindoles Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Antimicrob Chemother Year: 2015 Document type: Article Affiliation country: Belgium Country of publication: United kingdom
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Phospholipases / Vaccinia virus / Benzamides / Cowpox virus / Orthopoxvirus / Virus Assembly / Isoindoles Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Antimicrob Chemother Year: 2015 Document type: Article Affiliation country: Belgium Country of publication: United kingdom