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The cytotoxicity of 3-bromopyruvate in breast cancer cells depends on extracellular pH.
Azevedo-Silva, João; Queirós, Odília; Ribeiro, Ana; Baltazar, Fátima; Young, Ko H; Pedersen, Peter L; Preto, Ana; Casal, Margarida.
Affiliation
  • Azevedo-Silva J; *Centre of Molecular and Environmental Biology (CBMA), Department of Biology, University of Minho, Campus de Gualtar, Braga 4710-057, Portugal.
  • Queirós O; *Centre of Molecular and Environmental Biology (CBMA), Department of Biology, University of Minho, Campus de Gualtar, Braga 4710-057, Portugal.
  • Ribeiro A; *Centre of Molecular and Environmental Biology (CBMA), Department of Biology, University of Minho, Campus de Gualtar, Braga 4710-057, Portugal.
  • Baltazar F; ‡Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Campus de Gualtar, Braga 4710-057, Portugal.
  • Young KH; ║KoDiscovery, LLC, University of Maryland BioPark, Suite 502 E & F, 801 West Baltimore St., Baltimore, MD 21201, U.S.A.
  • Pedersen PL; ¶Departments of Biological Chemistry and Oncology, Member at Large, Sidney Kimmel Comprehensive Cancer Center, John Hopkins University, School of Medicine, Baltimore, MD 21205-2185, U.S.A.
  • Preto A; *Centre of Molecular and Environmental Biology (CBMA), Department of Biology, University of Minho, Campus de Gualtar, Braga 4710-057, Portugal.
  • Casal M; *Centre of Molecular and Environmental Biology (CBMA), Department of Biology, University of Minho, Campus de Gualtar, Braga 4710-057, Portugal.
Biochem J ; 467(2): 247-58, 2015 Apr 15.
Article in En | MEDLINE | ID: mdl-25641640
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyruvates / Breast Neoplasms / Cytotoxins / Tumor Microenvironment / Antineoplastic Agents Limits: Female / Humans Language: En Journal: Biochem J Year: 2015 Document type: Article Affiliation country: Portugal Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyruvates / Breast Neoplasms / Cytotoxins / Tumor Microenvironment / Antineoplastic Agents Limits: Female / Humans Language: En Journal: Biochem J Year: 2015 Document type: Article Affiliation country: Portugal Country of publication: United kingdom