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Targeting NADPH oxidase with a novel dual Nox1/Nox4 inhibitor attenuates renal pathology in type 1 diabetes.
Gorin, Yves; Cavaglieri, Rita C; Khazim, Khaled; Lee, Doug-Yoon; Bruno, Francesca; Thakur, Sachin; Fanti, Paolo; Szyndralewiez, Cédric; Barnes, Jeffrey L; Block, Karen; Abboud, Hanna E.
Affiliation
  • Gorin Y; Department of Medicine, The University of Texas Health Science Center, San Antonio, Texas; gorin@uthscsa.edu.
  • Cavaglieri RC; Department of Medicine, The University of Texas Health Science Center, San Antonio, Texas;
  • Khazim K; Department of Medicine, The University of Texas Health Science Center, San Antonio, Texas;
  • Lee DY; Department of Medicine, The University of Texas Health Science Center, San Antonio, Texas;
  • Bruno F; Department of Medicine, The University of Texas Health Science Center, San Antonio, Texas;
  • Thakur S; Department of Medicine, The University of Texas Health Science Center, San Antonio, Texas;
  • Fanti P; Department of Medicine, The University of Texas Health Science Center, San Antonio, Texas; Audie Leon Murphy Memorial Hospital Division, South Texas Veterans Health Care System, San Antonio, Texas; and.
  • Szyndralewiez C; Genkyotex SA, Geneva, Switzerland.
  • Barnes JL; Department of Medicine, The University of Texas Health Science Center, San Antonio, Texas; Audie Leon Murphy Memorial Hospital Division, South Texas Veterans Health Care System, San Antonio, Texas; and.
  • Block K; Department of Medicine, The University of Texas Health Science Center, San Antonio, Texas; Department of Medicine, The University of Texas Health Science Center, San Antonio, Texas;
  • Abboud HE; Department of Medicine, The University of Texas Health Science Center, San Antonio, Texas; Audie Leon Murphy Memorial Hospital Division, South Texas Veterans Health Care System, San Antonio, Texas; and.
Am J Physiol Renal Physiol ; 308(11): F1276-87, 2015 Jun 01.
Article in En | MEDLINE | ID: mdl-25656366
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Pyridines / NADPH Oxidases / Diabetes Mellitus, Type 1 / Enzyme Inhibitors / NADH, NADPH Oxidoreductases Limits: Animals Language: En Journal: Am J Physiol Renal Physiol Journal subject: FISIOLOGIA / NEFROLOGIA Year: 2015 Document type: Article Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Pyridines / NADPH Oxidases / Diabetes Mellitus, Type 1 / Enzyme Inhibitors / NADH, NADPH Oxidoreductases Limits: Animals Language: En Journal: Am J Physiol Renal Physiol Journal subject: FISIOLOGIA / NEFROLOGIA Year: 2015 Document type: Article Country of publication: United States