A potent anticancer agent of shikonin derivative targeting tubulin.

Baloch, Shahla Karim; Ma, Lin; Xu, Guo-Hua; Bai, Li-Fei; Zhao, Hua; Tang, Cheng-Yi; Pang, Yan-Jun; Yang, Rong-Wu; Wang, Xiao-Ming; Lu, Gui-Hua; Yang, Yong-Hua

Baloch, Shahla Karim; Ma, Lin; Xu, Guo-Hua; Bai, Li-Fei; Zhao, Hua; Tang, Cheng-Yi; Pang, Yan-Jun; Yang, Rong-Wu; Wang, Xiao-Ming; Lu, Gui-Hua; Yang, Yong-Hua.

Affiliation

Baloch SK; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, P.R. China; Department of Biotechnology, FCPD, Sindh Agriculture University, Tandojam, Pakistan.

Chirality ; 27(3): 274-80, 2015 Mar.

Article in En | MEDLINE | ID: mdl-25663187

Subject(s)

Antineoplastic Agents/pharmacology; Naphthoquinones/pharmacology; Tubulin Modulators/pharmacology; Apoptosis/drug effects; Cell Cycle Checkpoints/drug effects; Cell Line, Tumor; Humans; Inhibitory Concentration 50; Microtubules/chemistry; Microtubules/drug effects; Molecular Docking Simulation

Key words

anticancer; antitubulin; shikonin derivative

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Naphthoquinones / Tubulin Modulators / Antineoplastic Agents Limits: Humans Language: En Journal: Chirality Journal subject: BIOLOGIA MOLECULAR / QUIMICA Year: 2015 Document type: Article Affiliation country: Pakistan Country of publication: United States

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