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FGFR-Mediated Reactivation of MAPK Signaling Attenuates Antitumor Effects of Imatinib in Gastrointestinal Stromal Tumors.
Li, Fang; Huynh, Hung; Li, Xiaoyan; Ruddy, David A; Wang, Youzhen; Ong, Richard; Chow, Pierce; Qiu, Shumei; Tam, Angela; Rakiec, Daniel P; Schlegel, Robert; Monahan, John E; Huang, Alan.
Affiliation
  • Li F; Oncology Translational Research, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts. fang.li@novartis.com alan.huang@novartis.com.
  • Huynh H; Laboratory of Molecular Endocrinology, Division of Molecular and Cellular Research, National Cancer Centre, Singapore.
  • Li X; Oncology Translational Research, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Ruddy DA; Oncology Translational Research, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Wang Y; Oncology Translational Research, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Ong R; Laboratory of Molecular Endocrinology, Division of Molecular and Cellular Research, National Cancer Centre, Singapore.
  • Chow P; Laboratory of Molecular Endocrinology, Division of Molecular and Cellular Research, National Cancer Centre, Singapore.
  • Qiu S; Oncology Translational Research, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Tam A; Oncology Translational Research, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Rakiec DP; Oncology Translational Research, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Schlegel R; Oncology Translational Research, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Monahan JE; Oncology Translational Research, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Huang A; Oncology Translational Research, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts. fang.li@novartis.com alan.huang@novartis.com.
Cancer Discov ; 5(4): 438-51, 2015 Apr.
Article in En | MEDLINE | ID: mdl-25673643
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: MAP Kinase Signaling System / Gastrointestinal Stromal Tumors / Protein Kinase Inhibitors / ErbB Receptors / Imatinib Mesylate / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Cancer Discov Year: 2015 Document type: Article Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: MAP Kinase Signaling System / Gastrointestinal Stromal Tumors / Protein Kinase Inhibitors / ErbB Receptors / Imatinib Mesylate / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Cancer Discov Year: 2015 Document type: Article Country of publication: United States