The cAMP sensors, EPAC1 and EPAC2, display distinct subcellular distributions despite sharing a common nuclear pore localisation signal.

Parnell, Euan; Smith, Brian O; Yarwood, Stephen J

Parnell, Euan; Smith, Brian O; Yarwood, Stephen J.

Affiliation

Parnell E; Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, G12 8QQ, UK.
Smith BO; Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, G12 8QQ, UK.
Yarwood SJ; Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, G12 8QQ, UK. Electronic address: stephen.yarwood@glasgow.ac.uk.

Cell Signal ; 27(5): 989-96, 2015 May.

Article in En | MEDLINE | ID: mdl-25683912

Subject(s)

Cyclic AMP/metabolism; Guanine Nucleotide Exchange Factors/metabolism; Nuclear Localization Signals; Nuclear Pore/metabolism; Catalytic Domain; Guanine Nucleotide Exchange Factors/analysis; HEK293 Cells; Humans; Models, Molecular

Key words

EPAC; Nucleus; Targeting; cAMP

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cyclic AMP / Nuclear Localization Signals / Guanine Nucleotide Exchange Factors / Nuclear Pore Type of study: Prognostic_studies Limits: Humans Language: En Journal: Cell Signal Year: 2015 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

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