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Early postnatal ablation of the microRNA-processing enzyme, Drosha, causes chondrocyte death and impairs the structural integrity of the articular cartilage.
Kobayashi, T; Papaioannou, G; Mirzamohammadi, F; Kozhemyakina, E; Zhang, M; Blelloch, R; Chong, M W.
Affiliation
  • Kobayashi T; Endocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address: tkobayashi1@mgh.harvard.edu.
  • Papaioannou G; Endocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address: GPAPAIOANNOU@mgh.harvard.edu.
  • Mirzamohammadi F; Endocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address: FMIRZAMOHAMMADI@mgh.harvard.edu.
  • Kozhemyakina E; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: eKozhemyakina@dresourcesgroup.com.
  • Zhang M; Department of Orthopaedic Surgery, Boston Children's Hospital, Boston, MA 02115, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA. Electronic address: Minjie.Zhang@childrens.harvard.edu.
  • Blelloch R; The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: blellochr@stemcell.ucsf.edu.
  • Chong MW; Genomics and Immunology Laboratory, St. Vincent's Institute of Medical Research, and Department of Medicine, University of Melbourne, Fitzroy, VIC 3065, Australia. Electronic address: mchong@svi.edu.au.
Osteoarthritis Cartilage ; 23(7): 1214-20, 2015 Jul.
Article in En | MEDLINE | ID: mdl-25707934
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoarthritis / Cartilage, Articular / Chondrocytes / Ribonuclease III Type of study: Etiology_studies Limits: Animals Language: En Journal: Osteoarthritis Cartilage Journal subject: ORTOPEDIA / REUMATOLOGIA Year: 2015 Document type: Article Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoarthritis / Cartilage, Articular / Chondrocytes / Ribonuclease III Type of study: Etiology_studies Limits: Animals Language: En Journal: Osteoarthritis Cartilage Journal subject: ORTOPEDIA / REUMATOLOGIA Year: 2015 Document type: Article Country of publication: United kingdom