Disialoganglioside-specific human natural killer cells are effective against drug-resistant neuroblastoma.

Seidel, Diana; Shibina, Anastasia; Siebert, Nikolai; Wels, Winfried S; Reynolds, C Patrick; Huebener, Nicole; Lode, Holger N

Seidel, Diana; Shibina, Anastasia; Siebert, Nikolai; Wels, Winfried S; Reynolds, C Patrick; Huebener, Nicole; Lode, Holger N.

Affiliation

Seidel D; Department of Pediatric Hematology and Oncology, University Medicine Greifswald, Ferdinand-Sauerbruch Str., 17475, Greifswald, Germany.

Cancer Immunol Immunother ; 64(5): 621-34, 2015 May.

Article in En | MEDLINE | ID: mdl-25711293

Subject(s)

Drug Resistance, Neoplasm; Gangliosides/immunology; Immunotherapy, Adoptive/methods; Killer Cells, Natural/immunology; Neuroblastoma/therapy; Animals; Antibodies, Anti-Idiotypic/immunology; Cell Line; Cytotoxicity, Immunologic/immunology; Female; Gangliosides/genetics; Genetic Engineering; Humans; Mice; Mice, Inbred NOD; Neoplasm Transplantation; Neuroblastoma/immunology; Receptors, Antigen/biosynthesis; Receptors, Antigen/immunology; Single-Chain Antibodies/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Killer Cells, Natural / Immunotherapy, Adoptive / Drug Resistance, Neoplasm / Gangliosides / Neuroblastoma Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Cancer Immunol Immunother Journal subject: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Year: 2015 Document type: Article Affiliation country: Germany Country of publication: Germany

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