Effects of convection-enhanced delivery of bevacizumab on survival of glioma-bearing animals.

Wang, Weijun; Sivakumar, Walavan; Torres, Shering; Jhaveri, Niyati; Vaikari, Vijaya Pooja; Gong, Alex; Howard, Adam; Golden, Encouse B; Louie, Stan G; Schönthal, Axel H; Hofman, Florence M; Chen, Thomas C

Wang, Weijun; Sivakumar, Walavan; Torres, Shering; Jhaveri, Niyati; Vaikari, Vijaya Pooja; Gong, Alex; Howard, Adam; Golden, Encouse B; Louie, Stan G; Schönthal, Axel H; Hofman, Florence M; Chen, Thomas C.

Affiliation

Wang W; Departments of 1 Neurosurgery.

Neurosurg Focus ; 38(3): E8, 2015 Mar.

Article in En | MEDLINE | ID: mdl-25727230

Subject(s)

Angiogenesis Inhibitors/administration & dosage; Bevacizumab/administration & dosage; Brain Neoplasms/drug therapy; Brain Neoplasms/mortality; Glioma/drug therapy; Glioma/mortality; Animals; Antineoplastic Agents, Phytogenic/administration & dosage; Camptothecin/administration & dosage; Camptothecin/analogs & derivatives; Cell Line, Tumor; Dendritic Cells/pathology; Disease Models, Animal; Drug Delivery Systems; Drug Therapy, Combination; Humans; Irinotecan; Mice; Platelet Endothelial Cell Adhesion Molecule-1/metabolism; Time Factors; Xenograft Model Antitumor Assays

Key words

CED = convection-enhanced delivery; IP = intraperitoneal; IT = intratumoral; IV = intravenous; MVD = microvessel density; VEGF = vascular endothelial growth factor; VEGFR = VEGF receptor; bevacizumab; combination therapy; convection-enhanced delivery; glioma; monotherapy

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Angiogenesis Inhibitors / Bevacizumab / Glioma Type of study: Guideline / Prognostic_studies Limits: Animals / Humans Language: En Journal: Neurosurg Focus Journal subject: NEUROCIRURGIA Year: 2015 Document type: Article Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google