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Inhibitor of Aurora Kinase B Induces Differentially Cell Death and Polyploidy via DNA Damage Response Pathways in Neurological Malignancy: Shedding New Light on the Challenge of Resistance to AZD1152-HQPA.
Zekri, Ali; Ghaffari, Seyed H; Yaghmaie, Marjan; Estiar, Mehrdad Asghari; Alimoghaddam, Kamran; Modarressi, Mohammad Hossein; Ghavamzadeh, Ardeshir.
Affiliation
  • Zekri A; Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
  • Ghaffari SH; Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
  • Yaghmaie M; Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. shghaffari200@yahoo.com.
  • Estiar MA; Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
  • Alimoghaddam K; Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
  • Modarressi MH; Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
  • Ghavamzadeh A; Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mol Neurobiol ; 53(3): 1808-1823, 2016 Apr.
Article in En | MEDLINE | ID: mdl-25752998
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organophosphates / Polyploidy / Quinazolines / DNA Damage / Brain Neoplasms / Drug Resistance, Neoplasm / Protein Kinase Inhibitors / Aurora Kinase B Limits: Humans Language: En Journal: Mol Neurobiol Journal subject: BIOLOGIA MOLECULAR / NEUROLOGIA Year: 2016 Document type: Article Affiliation country: Iran Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organophosphates / Polyploidy / Quinazolines / DNA Damage / Brain Neoplasms / Drug Resistance, Neoplasm / Protein Kinase Inhibitors / Aurora Kinase B Limits: Humans Language: En Journal: Mol Neurobiol Journal subject: BIOLOGIA MOLECULAR / NEUROLOGIA Year: 2016 Document type: Article Affiliation country: Iran Country of publication: United States